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ZNF251 Knockout Cell Lines

Gene: ZNF251

Official Full Name: zinc finger protein 251provided by HGNC

Gene Summary: Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to act upstream of or within hematopoietic stem cell homeostasis. Predicted to be active in nucleus. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO23588 ZNF251 Knockout cell line (HeLa) Human ZNF251 1:3~1:6 Negative Online Inquiry
KO23589 ZNF251 Knockout cell line (HCT 116) Human ZNF251 1:2~1:4 Negative Online Inquiry
KO23590 ZNF251 Knockout cell line (HEK293) Human ZNF251 1:3~1:6 Negative Online Inquiry
KO23591 ZNF251 Knockout cell line (A549) Human ZNF251 1:3~1:4 Negative Online Inquiry

Background

ZNF251 Gene Knockout Cell Lines are genetically engineered cellular models designed to facilitate the in-depth study of the ZNF251 gene's functions and its implications in various biological processes. By utilizing CRISPR-Cas9 genome editing technology, these cell lines allow for the precise knockout of the ZNF251 gene, thereby enabling researchers to investigate the resultant phenotypic alterations, cellular pathways, and gene regulatory mechanisms associated with its absence.

The primary function of the ZNF251 Gene Knockout Cell Lines lies in their capacity to elucidate the role of ZNF251 in gene regulation, cellular differentiation, and potentially, its influence on disease states such as cancer. When researchers examine these knockout models, they can uncover critical insights into the gene's contribution to cellular homeostasis and its interactions with other genetic elements, thereby advancing our understanding of complex biological systems.

From a scientific standpoint, the ZNF251 knockout provides a valuable platform for dissecting gene function in both basic research and translational studies. In clinical settings, understanding ZNF251's role may reveal new biomarkers for disease or therapeutic targets for drug development. This product is particularly beneficial for laboratories focused on oncology, developmental biology, and epigenetics, where the nuanced effects of gene regulation are pivotal.

Compared to alternative models, which may involve overexpression techniques or lesser-defined knockdown approaches, ZNF251 Gene Knockout Cell Lines offer a more definitive insight into gene function via complete gene ablation. This specificity enhances experimental rigor and facilitates reproducibility, making the results more robust and reliable.

Research institutions and clinicians will find significant value in the ZNF251 Gene Knockout Cell Lines due to their ability to drive discoveries in gene function, disease mechanisms, and therapeutic interventions. Moreover, our company prides itself on providing high-quality, expertly crafted genetic tools backed by extensive validation, ensuring that our customers enhance their research outcomes with confidence and precision.

Please note that all services are for research use only. Not intended for any clinical use.

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