Gene: ZNF227
Official Full Name: zinc finger protein 227provided by HGNC
Gene Summary: Predicted to enable DNA-binding transcription activator activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to act upstream of or within negative regulation of DNA-templated transcription. Predicted to be active in nucleus. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO34477 | ZNF227 Knockout cell line (HeLa) | Human | ZNF227 | 1:3~1:6 | Negative | Online Inquiry |
KO34478 | ZNF227 Knockout cell line (HCT 116) | Human | ZNF227 | 1:2~1:4 | Negative | Online Inquiry |
KO34479 | ZNF227 Knockout cell line (HEK293) | Human | ZNF227 | 1:3~1:6 | Negative | Online Inquiry |
KO34480 | ZNF227 Knockout cell line (A549) | Human | ZNF227 | 1:3~1:4 | Negative | Online Inquiry |
ZNF227 Gene Knockout Cell Lines are sophisticated cellular tools derived from engineered cells that lack the expression of the ZNF227 gene, which encodes a zinc finger protein involved in various regulatory mechanisms within the cell. These knockout cell lines serve as pivotal models for studying gene function, signaling pathways, and the role of ZNF227 in cellular processes. By utilizing CRISPR-Cas9 technology, these cell lines have been meticulously crafted to ensure specific and efficient gene disruption, allowing researchers to explore the resultant phenotypic changes and molecular interactions.
The key functions of ZNF227 knockout cell lines include the ability to elucidate the gene’s role in cellular differentiation, transcriptional regulation, and potential involvement in oncogenic processes. The absence of ZNF227 offers a unique perspective into its contribution to developmental biology and tumorigenesis, thus facilitating targeted research initiatives in these areas. In clinical settings, these models are instrumental in evaluating the effectiveness of gene therapies and understanding disease mechanisms related to aberrant gene expression.
One of the primary advantages of ZNF227 Gene Knockout Cell Lines lies in their specificity and reliability, owing to our rigorous validation and optimization processes. Unlike alternative models that may exhibit off-target effects or variable expression levels, these knockout lines provide a stable and consistent platform for experimentation. This reliability is crucial for generating reproducible data, thereby bolstering the integrity of research findings.
For researchers and clinicians alike, ZNF227 Gene Knockout Cell Lines represent a valuable resource for advancing knowledge in gene function and its implications for human health. Whether investigating the mechanistic pathways of disease or exploring potential therapeutic interventions, these models empower users to achieve significant scientific advancements efficiently.
Our company boasts extensive expertise in developing high-quality biological reagents and tools, ensuring that products like ZNF227 Gene Knockout Cell Lines meet the rigorous standards of the scientific community. By equipping researchers with precise and reliable models, we are committed to facilitating impactful discoveries in molecular biology and genetics.
Please note that all services are for research use only. Not intended for any clinical use.
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