Gene: ZNF219
Official Full Name: zinc finger protein 219provided by HGNC
Gene Summary: This gene is a member of the Kruppel-like zinc finger gene family. The encoded protein functions as a transcriptional repressor of the high mobility group nucleosome binding domain 1 protein, which is associated with transcriptionally active chromatin. [provided by RefSeq, Apr 2017]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO22850 | ZNF219 Knockout cell line (HeLa) | Human | ZNF219 | 1:3~1:6 | Negative | Online Inquiry |
KO22851 | ZNF219 Knockout cell line (HCT 116) | Human | ZNF219 | 1:2~1:4 | Negative | Online Inquiry |
KO22852 | ZNF219 Knockout cell line (HEK293) | Human | ZNF219 | 1:3~1:6 | Negative | Online Inquiry |
KO22853 | ZNF219 Knockout cell line (A549) | Human | ZNF219 | 1:3~1:4 | Negative | Online Inquiry |
ZNF219 Gene Knockout Cell Lines are genetically engineered cell lines in which the ZNF219 gene has been disrupted or “knocked out” to facilitate the study of its functional roles and pathways in various biological contexts. This innovative tool enables researchers to dissect the contributions of ZNF219, a zinc-finger transcription factor, to cellular processes such as differentiation, proliferation, and various signaling pathways.
The primary mechanism of action for these cell lines lies in their ability to mimic gene loss-of-function models, allowing for an effective analysis of the resultant phenotypic changes. By creating a stable environment devoid of ZNF219 expression, researchers can investigate downstream effects on gene expression and cellular behavior, providing insights into the gene’s potential implications in diseases, particularly cancer and various genetic disorders.
The scientific importance of ZNF219 Gene Knockout Cell Lines in research and clinical settings is underscored by their applicability in elucidating molecular mechanisms associated with transcriptional regulation and gene expression. They serve as vital tools for drug development, enabling the identification of novel therapeutic targets and validating candidate drugs in a relevant cellular context.
Compared to alternative models, such as transient knockdown approaches or overexpression systems, these knockout cell lines offer a more stable and physiologically relevant platform for long-term studies. Their capability to provide consistent and reproducible results significantly enhances the reliability of experimental outcomes, which is particularly valuable in preclinical research.
For researchers and clinicians focused on understanding the complexities of gene function and regulation, ZNF219 Gene Knockout Cell Lines represent a powerful resource, driving discoveries that may lead to significant advancements in molecular biology and therapeutic interventions. With extensive expertise in genetic engineering and cellular biology, our company is committed to providing high-quality research tools that empower scientists to push the boundaries of their inquiries.
Please note that all services are for research use only. Not intended for any clinical use.
If your question is not addressed through these resources, you can fill out the online form below and we will answer your question as soon as possible.
There is no product in your cart. |
CD Biosynsis is a leading customer-focused biotechnology company dedicated to providing high-quality products, comprehensive service packages, and tailored solutions to support and facilitate the applications of synthetic biology in a wide range of areas.