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ZNF181 Knockout Cell Lines

Gene: ZNF181

Official Full Name: zinc finger protein 181provided by HGNC

Gene Summary: Zinc finger proteins have been shown to interact with nucleic acids and to have diverse functions. The zinc finger domain is a conserved amino acid sequence motif containing 2 specifically positioned cysteines and 2 histidines that are involved in coordinating zinc. Kruppel-related proteins form 1 family of zinc finger proteins. See MIM 604749 for additional information on zinc finger proteins.[supplied by OMIM, Jul 2003]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO34549 ZNF181 Knockout cell line (HeLa) Human ZNF181 1:3~1:6 Negative Online Inquiry
KO34550 ZNF181 Knockout cell line (HCT 116) Human ZNF181 1:2~1:4 Negative Online Inquiry
KO34551 ZNF181 Knockout cell line (HEK293) Human ZNF181 1:3~1:6 Negative Online Inquiry
KO34552 ZNF181 Knockout cell line (A549) Human ZNF181 1:3~1:4 Negative Online Inquiry

Background

ZNF181 Gene Knockout Cell Lines are specialized cell line models engineered to facilitate the study of the ZNF181 gene's role in various biological processes. ZNF181 encodes a zinc finger protein implicated in transcriptional regulation, making its knockout particularly valuable for understanding gene function as well as its potential involvement in disease states. By utilizing CRISPR-Cas9 technology, these cell lines exhibit complete ablation of the ZNF181 gene, enabling researchers to study downstream effects, compensatory mechanisms, and functional pathways without the interference of ZNF181 expression.

The primary function of the ZNF181 Gene Knockout Cell Lines lies in their ability to serve as a comparative platform for exploring the physiological and pathological roles of the ZNF181 gene. Researchers can investigate changes in cellular behavior, protein interactions, and signaling pathways to elucidate the gene's contribution to various conditions, such as cancer or developmental disorders. This provides crucial insights for understanding disease mechanisms at a cellular level.

Scientifically, ZNF181 knockout models are invaluable in both research and clinical settings. They enable the exploration of gene therapies, drug responses, and the identification of genetic targets for therapeutic intervention. By comparing knockout cells with wild-type counterparts, researchers can gather robust data regarding the gene's functional significance and therapeutic potential.

Compared to alternative models, ZNF181 Gene Knockout Cell Lines offer uniquely tailored conditions that allow for high specificity in targeting ZNF181. These models are created with precise genetic editing, ensuring reliability in experimental outcomes. Researchers gain complete confidence that observed phenotypic changes arise directly from the knockout rather than other genetic variabilities.

For researchers and clinicians, the value of ZNF181 Gene Knockout Cell Lines is clear: they are not only a tool for fundamental research but also promise to advance clinical applications in gene therapy and personalized medicine. Understanding the role of ZNF181 could unlock new pathways for treatment strategies across a spectrum of diseases.

Our company specializes in high-quality genetic models and will continue to deliver innovative products that align with the evolving needs of researchers and clinicians. Our expertise ensures that you receive cutting-edge tools for unparalleled scientific exploration.

Please note that all services are for research use only. Not intended for any clinical use.

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