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ZNF180 Knockout Cell Lines

Gene: ZNF180

Official Full Name: zinc finger protein 180provided by HGNC

Gene Summary: Zinc finger proteins have been shown to interact with nucleic acids and to have diverse functions. The zinc finger domain is a conserved amino acid sequence motif containing 2 specifically positioned cysteines and 2 histidines that are involved in coordinating zinc. Kruppel-related proteins form 1 family of zinc finger proteins. See MIM 604749 for additional information on zinc finger proteins.[supplied by OMIM, Jul 2002]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO34561 ZNF180 Knockout cell line (HeLa) Human ZNF180 1:3~1:6 Negative Online Inquiry
KO34562 ZNF180 Knockout cell line (HCT 116) Human ZNF180 1:2~1:4 Negative Online Inquiry
KO34563 ZNF180 Knockout cell line (HEK293) Human ZNF180 1:3~1:6 Negative Online Inquiry
KO34564 ZNF180 Knockout cell line (A549) Human ZNF180 1:3~1:4 Negative Online Inquiry

Background

ZNF180 Gene Knockout Cell Lines are genetically engineered, mammalian cell lines in which the ZNF180 gene has been deliberately disrupted or “knocked out.” This innovative biological product enables researchers to study the gene's functions, interactions, and associated pathways in various cellular contexts. The knockout of ZNF180 results in the alteration of its protein product, allowing scientists to explore the downstream effects of its absence, thereby providing insight into gene regulation mechanisms, cellular responses, and disease pathogenesis.

The functionality of ZNF180 Gene Knockout Cell Lines stems from advanced CRISPR-Cas9 technology, which facilitates precise gene editing by creating double-strand breaks at specific genomic loci. The cell's natural repair mechanisms then introduce insertions or deletions, leading to the knockout effect. This process not only enables researchers to dissect the biological role of ZNF180 but also offers the ability to model diseases related to its dysfunction, thus contributing to the understanding of disorders such as cancers and neurological conditions.

The scientific importance of these cell lines extends into both research and clinical settings. They are instrumental in deciphering cellular signaling pathways, drug responses, and genetic interactions, making them invaluable tools for pharmaceutical development and targeted therapeutics. Additionally, their use in innovative research can expedite translational medicine applications, potentially leading to breakthroughs in personalized medicine.

One primary advantage of ZNF180 Gene Knockout Cell Lines is the specificity and efficiency of the CRISPR-Cas9 knockout, which can outperform traditional gene disruption methods that may lack precision or lead to off-target effects. This precision ensures that results are reliable and reproducible, elevating the quality of research outcomes.

For researchers, clinicians, and biotechnology professionals, these cell lines provide a robust platform to investigate the ZNF180 gene’s involvement in disease mechanisms, contributing not just to advancements in scientific knowledge but also to the development of therapeutic strategies. At [Your Company Name], we specialize in providing high-quality biological products, supported by extensive expertise in genetic engineering and cellular biology, ensuring our customers access innovative solutions to enhance their research capabilities.

Please note that all services are for research use only. Not intended for any clinical use.

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