Gene: ZNF18
Official Full Name: zinc finger protein 18provided by HGNC
Gene Summary: Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO34719 | ZNF18 Knockout cell line (HeLa) | Human | ZNF18 | 1:3~1:6 | Negative | Online Inquiry |
KO34720 | ZNF18 Knockout cell line (HCT 116) | Human | ZNF18 | 1:2~1:4 | Negative | Online Inquiry |
KO34721 | ZNF18 Knockout cell line (HEK293) | Human | ZNF18 | 1:3~1:6 | Negative | Online Inquiry |
KO34722 | ZNF18 Knockout cell line (A549) | Human | ZNF18 | 1:3~1:4 | Negative | Online Inquiry |
ZNF18 Gene Knockout Cell Lines are specially engineered cellular models that have undergone precise gene editing to disrupt the ZNF18 gene, a key player in various biological pathways associated with cellular processes such as differentiation, proliferation, and apoptosis. By utilizing CRISPR/Cas9 technology, these cell lines provide researchers with the ability to study the functional role of the ZNF18 gene in a controlled environment, facilitating insights into its contributions in both normal physiology and disease states.
The primary mechanism by which ZNF18 gene knockout cell lines operate involves the removal or disruption of the ZNF18 gene, leading to the evaluation of downstream effects on gene expression and cellular behavior. This functional assessment enables scientists to elucidate the gene’s involvement in critical pathways and develop a deeper understanding of its role in oncogenesis, neurobiology, and metabolic disorders.
In terms of scientific importance, ZNF18 has been implicated in various pathologies, including certain cancers and neurodegenerative diseases. The use of these knockout cell lines in research accelerates the identification of molecular mechanisms driving disease progression, thus paving the way for potential therapeutic interventions. Furthermore, in clinical settings, such models significantly enhance the drug development process by providing relevant cellular contexts for testing targeted therapies.
The ZNF18 Gene Knockout Cell Lines stand out due to their high specificity and reproducibility, ensuring reliable experimental outcomes in comparison to traditional knockout models. Additionally, these cell lines are readily available and can be quickly integrated into existing workflows, allowing researchers to save time and resources.
For researchers and clinicians invested in the fields of genetics, oncology, or neurobiology, the ZNF18 Gene Knockout Cell Lines offer an invaluable tool for dissecting complex biological interactions. The commitment of our company to high-quality, scientifically robust products reflects our dedication to advancing biological research and contributing to groundbreaking discoveries. By leveraging our advanced genetic engineering techniques, we ensure that our cell lines facilitate impactful research outcomes and innovative clinical applications.
Please note that all services are for research use only. Not intended for any clinical use.
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