Gene: ZMYND10
Official Full Name: zinc finger MYND-type containing 10provided by HGNC
Gene Summary: This gene encodes a protein containing a MYND-type zinc finger domain that likely functions in assembly of the dynein motor. Mutations in this gene can cause primary ciliary dyskinesia. This gene is also considered a tumor suppressor gene and is often mutated, deleted, or hypermethylated and silenced in cancer cells. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2015]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO22610 | ZMYND10 Knockout cell line (HCT 116) | Human | ZMYND10 | 1:2~1:4 | Negative | Online Inquiry |
KO22611 | ZMYND10 Knockout cell line (HEK293) | Human | ZMYND10 | 1:3~1:6 | Negative | Online Inquiry |
ZMYND10 Gene Knockout Cell Lines are genetically engineered cell models designed to facilitate detailed studies of the ZMYND10 gene, a critical regulator of cellular processes and gene expression. By utilizing CRISPR-Cas9 technology, these cell lines allow for precise deletions of the ZMYND10 gene, enabling researchers to investigate its role in various biological functions, including cancer progression, epigenetic regulation, and cellular stress responses.
The primary function of ZMYND10 Gene Knockout Cell Lines is to serve as a valuable tool for understanding the consequences of ZMYND10 loss on cellular behavior. Upon knockout, these cell lines demonstrate altered gene expression patterns, enhanced cell proliferation, or changes in apoptosis rates, depending on the context. Such functional insights can enlighten research into disease mechanisms and therapeutic targets.
The scientific importance of these cell lines extends into both basic and applied research. In a clinical setting, investigating ZMYND10’s role could illuminate novel pathways for biomarker discovery and therapeutic intervention. With applications spanning oncology, neurology, and developmental biology, these models serve as a bridge between laboratory findings and potential clinical applications.
The unique selling points of ZMYND10 Gene Knockout Cell Lines lie in their specificity, reliability, and versatility. Unlike traditional knockout methods, the CRISPR-Cas9 approach minimizes off-target effects and enhances the accuracy of gene editing. Moreover, these cell lines are readily amenable to various experimental conditions, making them suitable for high-throughput screening and functional assays.
Value is further amplified by our commitment to quality and support. As experts in genetic engineering, we ensure that each cell line undergoes rigorous validation and characterization, guaranteeing reproducibility in research endeavors. With ZMYND10 Gene Knockout Cell Lines, researchers and clinicians can rest assured that they are equipped with a robust tool poised to advance their work in understanding and manipulating gene function.
Please note that all services are for research use only. Not intended for any clinical use.
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