Gene: ZFYVE28
Official Full Name: zinc finger FYVE-type containing 28provided by HGNC
Gene Summary: Enables phosphatidylinositol-3-phosphate binding activity. Involved in negative regulation of epidermal growth factor-activated receptor activity. Located in cytosol and early endosome membrane. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO12370 | ZFYVE28 Knockout cell line (HeLa) | Human | ZFYVE28 | 1:3~1:6 | Negative | Online Inquiry |
KO12371 | ZFYVE28 Knockout cell line (HCT 116) | Human | ZFYVE28 | 1:2~1:4 | Negative | Online Inquiry |
KO12372 | ZFYVE28 Knockout cell line (HEK293) | Human | ZFYVE28 | 1:3~1:6 | Negative | Online Inquiry |
KO12373 | ZFYVE28 Knockout cell line (A549) | Human | ZFYVE28 | 1:3~1:4 | Negative | Online Inquiry |
ZFYVE28 Gene Knockout Cell Lines are specifically engineered cellular models that facilitate the comprehensive study of the ZFYVE28 gene, known for its roles in cellular processes such as endosomal trafficking and signaling pathways. These cell lines have been created using advanced CRISPR/Cas9 technology, ensuring precise disruption of the ZFYVE28 gene, enabling researchers to investigate its function in various biological contexts effectively.
The primary mechanism of these knockout cell lines involves the targeted alteration of the ZFYVE28 gene, which leads to the absence of functional protein. This disruption allows investigators to analyze cellular responses, phenotype variations, and molecular interactions that arise in the absence of ZFYVE28, thereby providing critical insights into its contributions to normal physiology and disease states.
Scientific research values ZFYVE28 Gene Knockout Cell Lines for their applications in fields such as developmental biology, cancer research, and neurobiology. By elucidating the biological roles of ZFYVE28, these models can contribute to understanding complex diseases where dysregulation of gene expression plays a significant role. Additionally, these cell lines hold promise for drug discovery and therapeutic interventions, as they can be employed to screen for compounds that may restore normal function or inhibit deleterious pathways associated with ZFYVE28 dysfunction.
A unique advantage of ZFYVE28 Gene Knockout Cell Lines lies in the specificity and reliability of CRISPR/Cas9 technology, which minimizes off-target effects and ensures reproducible results. Unlike traditional knockdown approaches, these knockout models provide definitive insights into gene function, making them a superior choice for those aiming to achieve rigorous scientific results.
Researchers and clinicians stand to gain significantly from these cell lines, as they support a more profound understanding of cellular mechanisms and their implications in health and disease. The accessibility and robustness of this tool make it invaluable for advancing scientific knowledge and therapeutic strategies.
Our company specializes in providing high-quality biological products, including expertly engineered cell lines that serve the needs of both researchers and clinicians. With a commitment to scientific innovation, we strive to empower our customers with the tools required to drive breakthrough discoveries in their respective fields.
Please note that all services are for research use only. Not intended for any clinical use.
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