Gene: ZFYVE27
Official Full Name: zinc finger FYVE-type containing 27provided by HGNC
Gene Summary: This gene encodes a protein with several transmembrane domains, a Rab11-binding domain and a lipid-binding FYVE finger domain. The encoded protein appears to promote neurite formation. A mutation in this gene has been reported to be associated with hereditary spastic paraplegia, however the pathogenicity of the mutation, which may simply represent a polymorphism, is unclear. [provided by RefSeq, Mar 2010]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO30395 | ZFYVE27 Knockout cell line (HeLa) | Human | ZFYVE27 | 1:3~1:6 | Negative | Online Inquiry |
KO30396 | ZFYVE27 Knockout cell line (HCT 116) | Human | ZFYVE27 | 1:2~1:4 | Negative | Online Inquiry |
KO30397 | ZFYVE27 Knockout cell line (HEK293) | Human | ZFYVE27 | 1:3~1:6 | Negative | Online Inquiry |
KO30398 | ZFYVE27 Knockout cell line (A549) | Human | ZFYVE27 | 1:3~1:4 | Negative | Online Inquiry |
ZFYVE27 Gene Knockout Cell Lines are advanced biological tools designed to facilitate in-depth studies of genetic function and the underlying mechanisms of various diseases. These cell lines have been specifically engineered to disable the ZFYVE27 gene, resulting in a knockout model that allows researchers to explore the gene's role in cellular processes such as regulation of apoptosis, cell signaling, and intracellular transport.
The key function of these knockout cell lines lies in their ability to mimic disease states associated with ZFYVE27 dysfunction, thus providing insights into the gene's contributions to various conditions, including neurodegenerative diseases and cancer. Through the use of CRISPR-Cas9 gene-editing technology, ZFYVE27 has been precisely targeted to ensure complete gene knockout, allowing researchers to study related pathways and interactions in a controlled environment. The loss of this specific gene enables the evaluation of compensatory mechanisms within the cell, offering a comprehensive view of disease pathology and potential therapeutic targets.
The scientific importance of ZFYVE27 Gene Knockout Cell Lines extends to both research and clinical applications, empowering scientists to investigate gene functions, validate drug targets, and assess the efficacy of new treatments in a relevant context. These cell lines can also serve as a foundation for developing personalized medicine strategies, helping to tailor treatments based on the specific genetic profiles of patients.
Compared to other knockout models, the ZFYVE27 Gene Knockout Cell Lines stand out due to their high specificity, ease of use, and reproducibility across experiments. They provide a crucial resource for researchers seeking reliable data on the gene's involvement in key biological processes, thus reducing variability often associated with animal models.
For researchers and clinicians, investing in ZFYVE27 Gene Knockout Cell Lines means gaining access to a tool that streamlines experiments and enriches data quality. By leveraging these cell lines, scientists can accelerate their understanding of complex genetic interactions and translation into clinical applications, ultimately enhancing their research output.
As a leading provider of cutting-edge biological tools, our company offers ZFYVE27 Gene Knockout Cell Lines backed by extensive scientific expertise and a commitment to supporting advancements in biological research. Our products are designed with the highest standards, ensuring that researchers receive reliable and innovative solutions tailored to their specific needs.
Please note that all services are for research use only. Not intended for any clinical use.
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