Gene: ZFYVE21
Official Full Name: zinc finger FYVE-type containing 21provided by HGNC
Gene Summary: Predicted to enable metal ion binding activity. Predicted to be located in endosome and focal adhesion. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO12374 | ZFYVE21 Knockout cell line (HeLa) | Human | ZFYVE21 | 1:3~1:6 | Negative | Online Inquiry |
KO12375 | ZFYVE21 Knockout cell line (HCT 116) | Human | ZFYVE21 | 1:2~1:4 | Negative | Online Inquiry |
KO12376 | ZFYVE21 Knockout cell line (HEK293) | Human | ZFYVE21 | 1:3~1:6 | Negative | Online Inquiry |
KO12377 | ZFYVE21 Knockout cell line (A549) | Human | ZFYVE21 | 1:3~1:4 | Negative | Online Inquiry |
ZFYVE21 Gene Knockout Cell Lines are meticulously engineered cellular models designed to investigate the functional role of the ZFYVE21 gene in various biological processes, particularly within the context of cell signaling, autophagy, and disease pathology. These knockout cell lines are generated through advanced CRISPR-Cas9 gene-editing technology, effectively enabling the precise disruption of ZFYVE21 expression. By silencing this gene, researchers can delve into its contributions to cellular dynamics and its implications in health and disease.
Central to the functionality of the ZFYVE21 knockout cell lines is their ability to facilitate the study of gene function through a "loss of function" paradigm. This approach allows scientists to observe phenotypic changes that occur when ZFYVE21 is absent, providing insights into its role in mechanisms such as endosomal trafficking and cellular responses to stress. The detailed analysis of these pathways is particularly valuable in fields like cancer research, neurodegenerative diseases, and metabolic disorders, where ZFYVE21 may act as a critical modulator.
The scientific importance of these cell lines lies in their potential to uncover novel therapeutic targets and biomarkers related to diseases associated with aberrant ZFYVE21 activity. Moreover, they serve as robust models for drug screening and development, allowing researchers to test compounds targeting pathways influenced by ZFYVE21 disruption. Compared to traditional gene knockout methods, the generation of ZFYVE21 knockout cell lines via CRISPR offers higher efficiency, specificity, and reproducibility, thus ensuring more reliable results.
For researchers and clinicians seeking to explore the intricate roles of ZFYVE21 in various biological contexts, these knockout cell lines provide an invaluable resource. Their use can lead to groundbreaking discoveries in molecular biology, advancing our understanding of numerous pathological states. Additionally, our company prides itself on its expertise in developing cutting-edge biological products, ensuring that our offerings are of the highest quality and tailored to meet the rigorous demands of modern scientific research. With ZFYVE21 Gene Knockout Cell Lines, we empower the scientific community to push the boundaries of knowledge and innovation.
Please note that all services are for research use only. Not intended for any clinical use.
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