Gene: ZFYVE19
Official Full Name: zinc finger FYVE-type containing 19provided by HGNC
Gene Summary: Enables phosphatidylinositol-3-phosphate binding activity. Involved in midbody abscission; mitotic cytokinesis checkpoint signaling; and negative regulation of cytokinesis. Located in centrosome; cleavage furrow; and midbody. Implicated in progressive familial intrahepatic cholestasis. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO24445 | ZFYVE19 Knockout cell line (HeLa) | Human | ZFYVE19 | 1:3~1:6 | Negative | Online Inquiry |
KO24446 | ZFYVE19 Knockout cell line (HCT 116) | Human | ZFYVE19 | 1:2~1:4 | Negative | Online Inquiry |
KO24447 | ZFYVE19 Knockout cell line (HEK293) | Human | ZFYVE19 | 1:3~1:6 | Negative | Online Inquiry |
KO24448 | ZFYVE19 Knockout cell line (A549) | Human | ZFYVE19 | 1:3~1:4 | Negative | Online Inquiry |
ZFYVE19 Gene Knockout Cell Lines are innovative cellular models that have been specifically engineered to lack the expression of the ZFYVE19 gene. This genetic modification allows researchers to study the physiological and pathological roles of ZFYVE19 in various biological systems. By utilizing the CRISPR-Cas9 gene-editing technology, these cell lines provide a precise tool for investigating the gene's involvement in cellular processes, such as migration, apoptosis, and signaling pathways.
The key function of ZFYVE19 Knockout Cell Lines lies in their ability to elucidate the role of ZFYVE19 in disease mechanisms, particularly in cancer and neurodegenerative disorders. Researchers can observe the phenotypic changes and molecular alterations that result from this knockout, facilitating a deeper understanding of ZFYVE19's contributions to cellular function. This can lead to the identification of potential therapeutic targets and aid in the discovery of novel drug candidates.
Scientifically, ZFYVE19 Knockout Cell Lines are invaluable in both research and clinical applications. Their use extends to drug screening, functional genomics, and the development of personalized medicine strategies. Compared to conventional cell lines that may express ZFYVE19, these knockout lines offer a unique opportunity to create a clearer picture of the gene's role without confounding factors.
What sets ZFYVE19 Gene Knockout Cell Lines apart from alternative systems is the specificity and reliability of the CRISPR-Cas9 modification, which ensures a complete knockout without off-target effects. This specificity increases the reproducibility of results, making these cell lines a trusted choice for rigorous scientific investigation.
For researchers and clinicians seeking to further their understanding of the ZFYVE19 gene and its cellular implications, these knockout cell lines represent a critical resource. Their availability can dramatically enhance the quality of research outcomes and pave the way for innovative therapeutic strategies. Our commitment to providing high-quality biological products is founded on years of expertise in genetic engineering and cell biology, ensuring that you receive reliable and effective research tools for advancing your work.
Please note that all services are for research use only. Not intended for any clinical use.
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