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ZER1 Knockout Cell Lines

Gene: ZER1

Official Full Name: zyg-11 related cell cycle regulatorprovided by HGNC

Gene Summary: This gene encodes a subunit of an E3 ubiquitin ligase complex that may be involved in meiosis. The encoded protein contains three leucine-rich repeat motifs. [provided by RefSeq, Nov 2012]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO02493 ZER1 Knockout cell line (HeLa) Human ZER1 1:3~1:6 Negative Online Inquiry
KO02494 ZER1 Knockout cell line (HCT 116) Human ZER1 1:2~1:4 Negative Online Inquiry
KO02495 ZER1 Knockout cell line (HEK293) Human ZER1 1:3~1:6 Negative Online Inquiry
KO02496 ZER1 Knockout cell line (A549) Human ZER1 1:3~1:4 Negative Online Inquiry

Background

ZER1 Gene Knockout Cell Lines are advanced genetically modified models designed to eliminate the expression of the ZER1 gene, a critical component involved in various cellular processes. These cell lines utilize sophisticated CRISPR/Cas9 gene editing technologies to achieve precise gene disruption, allowing researchers to study the resulting phenotypic and biochemical changes in vitro. By creating a knockout model, scientists can explore the functional roles of ZER1 in cellular contexts, determining its impact on pathways such as cell proliferation, differentiation, and stress response.

The primary mechanism by which the ZER1 Gene Knockout Cell Lines operate involves the targeted introduction of double-strand breaks in the DNA at specific loci. Following this, the cell’s natural repair machinery attempts to mend the break, often leading to insertions or deletions that disrupt the gene's coding sequence. This process not only enables the effective ablation of ZER1 expression but also permits the examination of compensatory mechanisms that other genes may implement in response.

In terms of scientific importance, ZER1 Gene Knockout Cell Lines serve as indispensable tools across various research fields, including cancer biology, developmental biology, and pharmacology. They are instrumental in elucidating the biological roles of the ZER1 gene and its potential involvement in disease states, thereby contributing to the identification of novel therapeutic targets. Additionally, these models provide invaluable insights into the effects of gene modulation on cellular behavior, which is crucial for drug discovery and the development of targeted therapies.

Compared to other genetic models, such as RNA interference-based systems or traditional knockout methods, the ZER1 Gene Knockout Cell Lines offer unparalleled specificity and efficiency. The CRISPR/Cas9 technology employed ensures a high knockout rate while minimizing off-target effects, thereby enhancing the reliability of experimental outcomes. Furthermore, these cell lines are provided with a user-friendly application protocol, enabling researchers to integrate them seamlessly into existing workflows with minimal technical hurdles.

Due to the growing relevance of the ZER1 gene in various pathological conditions, the ZER1 Gene Knockout Cell Lines are a valuable addition to the research toolkit for scientists seeking to delve deeper into gene function and regulation. They empower researchers and clinicians alike to generate critical data that drive innovations in molecular medicine and therapeutic interventions.

Our company, rooted in extensive expertise in genetic engineering and cell biology, is dedicated to providing high-quality biological products that facilitate cutting-edge research. With a commitment to excellence and a focus on innovation, we are proud to support the scientific community with solutions like the ZER1 Gene Knockout Cell Lines, designed to advance discovery and improve human health.

Please note that all services are for research use only. Not intended for any clinical use.

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