Gene: ZBTB8A
Official Full Name: zinc finger and BTB domain containing 8Aprovided by HGNC
Gene Summary: Enables several functions, including DNA-binding transcription repressor activity, RNA polymerase II-specific; RNA polymerase II-specific DNA-binding transcription factor binding activity; and transcription coactivator binding activity. Involved in negative regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO12494 | ZBTB8A Knockout cell line (HeLa) | Human | ZBTB8A | 1:3~1:6 | Negative | Online Inquiry |
KO12495 | ZBTB8A Knockout cell line (HCT 116) | Human | ZBTB8A | 1:2~1:4 | Negative | Online Inquiry |
KO12496 | ZBTB8A Knockout cell line (HEK293) | Human | ZBTB8A | 1:3~1:6 | Negative | Online Inquiry |
KO12497 | ZBTB8A Knockout cell line (A549) | Human | ZBTB8A | 1:3~1:4 | Negative | Online Inquiry |
ZBTB8A Gene Knockout Cell Lines are advanced cellular models engineered to specifically disrupt the ZBTB8A gene, an essential transcription factor involved in various biological processes, including immune response regulation and cellular differentiation. By employing the CRISPR-Cas9 genome-editing technology, these cell lines allow researchers to achieve precise and efficient gene knockout, thereby facilitating the study of gene function and its implications in health and disease.
The primary function of ZBTB8A Gene Knockout Cell Lines involves elucidating the role of ZBTB8A in cellular pathways, including its impact on gene expression and signaling mechanisms. With the ability to assess phenotypic changes and molecular interactions post-knockout, researchers can gain insights into how the disruption of ZBTB8A affects cellular behavior, immune responses, and potential pathologies linked to dysregulation of this gene, notably in cancer and autoimmune diseases.
From a scientific standpoint, these cell lines have significant implications in both basic and applied research settings. They enable targeted investigations into the therapeutic potential of modulating ZBTB8A activity, which could lead to innovative treatment strategies for various diseases. Additionally, these models are invaluable for drug screening, biomarker discovery, and illuminating the intricate gene networks that ZBTB8A regulates.
Compared to conventional gene knockout methods, ZBTB8A Gene Knockout Cell Lines offer enhanced specificity and reproducibility, reducing off-target effects and allowing more accurate experimental outcomes. Their ready-to-use nature saves researchers time and resources, streamlining workflows in laboratories and accelerating the pace of discovery.
The value of ZBTB8A Gene Knockout Cell Lines lies in their ability to transform research paradigms, offering a powerful tool for scientists looking to unravel complex biological questions or develop novel therapeutic approaches. With a commitment to innovation and excellence, our company leverages cutting-edge technologies and rigorous scientific principles to deliver high-quality products that empower researchers and clinicians in their pursuit of knowledge and breakthroughs.
Please note that all services are for research use only. Not intended for any clinical use.
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