ZBTB20 Knockout Cell Lines

Gene: ZBTB20

Official Full Name: zinc finger and BTB domain containing 20provided by HGNC

Gene Summary: This gene, which was initially designated as dendritic cell-derived BTB/POZ zinc finger (DPZF), belongs to a family of transcription factors with an N-terminal BTB/POZ domain and a C-terminal DNA-bindng zinc finger domain. The BTB/POZ domain is a hydrophobic region of approximately 120 aa which mediates association with other BTB/POZ domain-containing proteins. This gene acts as a transcriptional repressor and plays a role in many processes including neurogenesis, glucose homeostasis, and postnatal growth. Mutations in this gene have been associated with Primrose syndrome as well as the 3q13.31 microdeletion syndrome. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Feb 2017]

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Products Background

Products

Catalog Number	Product Name	Species	Gene	Passage ratio	Mycoplasma testing	Price
KO28273	ZBTB20 Knockout cell line (HCT 116)	Human	ZBTB20	1:2~1:4	Negative	Online Inquiry

Background

ZBTB20 Gene Knockout Cell Lines are specifically engineered cellular models designed to facilitate the study of the ZBTB20 gene, which encodes a member of the zinc finger transcription factor family. These cell lines have undergone precise gene editing to insert a knockout mutation, effectively disabling the ZBTB20 gene and enabling researchers to elucidate its biological roles by examining the resultant phenotypic changes.

The primary function of ZBTB20 in cellular processes relates to its regulation of gene expression involved in various developmental pathways and neurological functions. By utilizing these knockout cell lines, researchers can investigate the downstream effects of ZBTB20 loss, contributing to a more comprehensive understanding of its involvement in diseases such as neurodevelopmental disorders, making them valuable tools for both research and clinical transfer applications.

The scientific importance of ZBTB20 Gene Knockout Cell Lines lies in their versatility across different experimental setups, ranging from basic molecular biology to advanced therapeutic investigations. The elucidation of ZBTB20 function can pave the way for the identification of novel targets for drug development, thereby enhancing the potential for therapeutic interventions in related pathologies.

One key advantage of our ZBTB20 Gene Knockout Cell Lines compared to alternative models is their high specificity and reproducibility, offering researchers a robust platform for consistent experimental results. Additionally, our lines are validated by rigorous quality control protocols, ensuring reliable performance that can accelerate research timelines and outcomes.

The value of these cell lines extends beyond traditional research environments, as they empower clinicians and biotechnologists to explore innovative solutions for disease intervention through translational research. Given our company’s extensive expertise in genomic editing technologies and our commitment to advancing biological research tools, we provide the scientific community with cutting-edge products that foster breakthroughs in genetic research.

Please note that all services are for research use only. Not intended for any clinical use.

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