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YWHAB Knockout Cell Lines

Gene: YWHAB

Official Full Name: tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein betaprovided by HGNC

Gene Summary: This gene encodes a protein belonging to the 14-3-3 family of proteins, members of which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals. The encoded protein has been shown to interact with RAF1 and CDC25 phosphatases, suggesting that it may play a role in linking mitogenic signaling and the cell cycle machinery. Two transcript variants, which encode the same protein, have been identified for this gene. [provided by RefSeq, Jul 2008]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO10116 YWHAB Knockout cell line (HeLa) Human YWHAB 1:3~1:6 Negative Online Inquiry
KO10117 YWHAB Knockout cell line (HCT 116) Human YWHAB 1:2~1:4 Negative Online Inquiry
KO10118 YWHAB Knockout cell line (HEK293) Human YWHAB 1:3~1:6 Negative Online Inquiry
KO10119 YWHAB Knockout cell line (A549) Human YWHAB 1:3~1:4 Negative Online Inquiry

Background

YWHAB Gene Knockout Cell Lines are a specialized suite of genetically modified cells designed to study the functional role of the YWHAB gene, which encodes the 14-3-3β protein—a critical regulator of various cellular processes such as signal transduction, apoptosis, and cell cycle control. These cell lines are engineered to lack the YWHAB gene, providing a powerful tool for elucidating its biological functions and interactions in a controlled setting.

The mechanism underlying the effectiveness of YWHAB Gene Knockout Cell Lines lies in their ability to mimic the genetic disruption observed in human diseases associated with YWHAB dysregulation, thus serving as a model for studying the consequences of its absence. By investigating these knockout cells, researchers can gain insights into the pathways impacted by the loss of YWHAB, explore potential compensatory mechanisms, and evaluate therapeutic strategies targeting associated diseases.

In terms of scientific importance, these cell lines hold significant value in both research and clinical settings. They allow for the identification of novel drug targets, the validation of biomarkers associated with cancer and other disorders, and the investigation of the molecular underpinnings of YWHAB-related conditions. This makes them especially valuable for researchers in fields such as oncology, neurology, and metabolic syndrome.

Compared to alternative systems, YWHAB Gene Knockout Cell Lines offer a unique advantage of specific, reliable gene disruption that can be maintained under stable growth conditions. This specificity ensures that results obtained from experiments are directly attributable to the absence of the YWHAB gene rather than non-specific effects seen in other gene-editing approaches.

Investing in YWHAB Gene Knockout Cell Lines provides researchers and clinicians with a robust platform to advance their studies, drive innovation, and ultimately work towards breakthrough therapeutic solutions. As leading experts in the field of biological products, our company is committed to providing high-quality, validated cell lines that meet stringent scientific standards, supporting your research endeavors with both precision and reliability.

Please note that all services are for research use only. Not intended for any clinical use.

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