Gene: Ythdc2
Official Full Name: YTH domain containing 2provided by MGI
Gene Summary: Enables 3'-5' RNA helicase activity; N6-methyladenosine-containing RNA reader activity; and RNA binding activity. Involved in germline cell cycle switching, mitotic to meiotic cell cycle; oocyte development; and spermatid development. Located in cytoplasm and ribonucleoprotein granule. Is expressed in brain; gonad; intestine; and liver. Orthologous to human YTHDC2 (YTH N6-methyladenosine RNA binding protein C2). [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO12520 | YTHDC2 Knockout cell line (HeLa) | Human | YTHDC2 | 1:3~1:6 | Negative | Online Inquiry |
KO12521 | YTHDC2 Knockout cell line (HCT 116) | Human | YTHDC2 | 1:2~1:4 | Negative | Online Inquiry |
KO12522 | YTHDC2 Knockout cell line (HEK293) | Human | YTHDC2 | 1:3~1:6 | Negative | Online Inquiry |
KO12523 | YTHDC2 Knockout cell line (A549) | Human | YTHDC2 | 1:3~1:4 | Negative | Online Inquiry |
Ythdc2 Gene Knockout Cell Lines are genetically engineered cell lines that have been specifically designed to disrupt the Ythdc2 gene, which encodes a critical RNA-binding protein involved in post-transcriptional regulation. These cell lines serve as an invaluable tool for researchers exploring RNA metabolism, gene expression control, and cellular responses to stress. The knockout of Ythdc2 allows scientists to investigate the downstream effects of disrupted RNA interactions and to elucidate the role of this gene in various biological pathways, particularly those related to mRNA stability and translation.
These cell lines provide a robust model to study the functional implications of Ythdc2 depletion. By utilizing CRISPR/Cas9 technology, the gene knockout is precise, enabling researchers to generate reproducible and reliable results. This level of specificity is essential for key experimental designs that require the dissection of complex cellular mechanisms, including cancer biology, neurobiology, and developmental studies.
The scientific importance of Ythdc2 Gene Knockout Cell Lines extends into both research and clinical settings, where they can be used to identify potential therapeutic targets for diseases linked to aberrant RNA processing. In drug discovery, for instance, understanding the molecular mechanisms surrounding Ythdc2 can inform the development of novel RNA-targeted therapies.
One of the primary advantages of our Ythdc2 Gene Knockout Cell Lines is their straightforward implementation in a variety of experimental contexts, coupled with a high level of consistency and reliability compared to other genetic manipulations, such as transient knockdowns which can yield variable results. Additionally, we offer a comprehensive support package, including guidance on experimental design and troubleshooting, ensuring that researchers can fully capitalize on the potential of these cell lines.
For researchers and clinicians aimed at advancing their understanding of gene function and its implications in health and disease, the Ythdc2 Gene Knockout Cell Lines present a unique, powerful resource. Our commitment to quality and innovation in biological products, backed by years of expertise in genetic engineering, ensures that you are equipping your laboratory with the tools necessary to drive impactful discoveries.
Please note that all services are for research use only. Not intended for any clinical use.
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