Gene: XYLB
Official Full Name: xylulokinaseprovided by HGNC
Gene Summary: The protein encoded by this gene shares 22% sequence identity with Hemophilus influenzae xylulokinase, and even higher identity to other gene products in C.elegans (45%) and yeast (31-35%), which are thought to belong to a family of enzymes that include fucokinase, gluconokinase, glycerokinase and xylulokinase. These proteins play important roles in energy metabolism. [provided by RefSeq, Aug 2009]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO32477 | XYLB Knockout cell line (HeLa) | Human | XYLB | 1:3~1:6 | Negative | Online Inquiry |
KO32478 | XYLB Knockout cell line (HCT 116) | Human | XYLB | 1:2~1:4 | Negative | Online Inquiry |
KO32479 | XYLB Knockout cell line (HEK293) | Human | XYLB | 1:3~1:6 | Negative | Online Inquiry |
KO32480 | XYLB Knockout cell line (A549) | Human | XYLB | 1:3~1:4 | Negative | Online Inquiry |
XYLB Gene Knockout Cell Lines are highly specialized cellular models engineered to lack the expression of the XYLB gene, which encodes for xylosyltransferase, an enzyme pivotal in the biosynthesis of glycosaminoglycan chains in proteoglycans. These knockout cell lines are invaluable for research involving cellular metabolism, development, and disease modeling, as they allow scientists to elucidate the role of the XYLB gene in various biological processes.
The primary function of these cell lines is to provide a controlled environment to study the consequences of XYLB gene disruption. By utilizing CRISPR-Cas9 technology, these cell lines exhibit a complete absence of XYLB activity, enabling researchers to analyze the resultant phenotypic changes. This is particularly useful in investigating pathways associated with skeletal development, cell signaling, and ECM (extracellular matrix) composition.
Scientifically, these cell lines hold considerable importance in both research and clinical applications. In cancer biology, for instance, understanding the modulation of the glycosaminoglycan synthesis pathways is paramount, as it may reveal novel therapeutic targets. Furthermore, these models facilitate studies in regenerative medicine and tissue engineering, where the effects of altered proteoglycan synthesis can dramatically influence cell behavior and tissue integrity.
The XYLB Gene Knockout Cell Lines stand out from alternative models due to their precise gene editing, ensuring complete knockout efficiency and reproducibility in experimental outcomes. This rigor allows for more reliable data, reducing variability that can confound experimental interpretations. Researchers and clinicians can confidently utilize these cell lines for high-stakes experiments, knowing they represent a well-characterized and validated research tool.
By investing in XYLB Gene Knockout Cell Lines, users gain access to a cutting-edge resource that enhances research quality and accelerates discoveries in the biosciences. Our company prides itself on its commitment to excellence in product development and scientific innovation, ensuring that we offer high-quality, ready-to-use biological resources that empower researchers and advance the frontiers of science.
Please note that all services are for research use only. Not intended for any clinical use.
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