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XPR1 Knockout Cell Lines

Gene: XPR1

Official Full Name: xenotropic and polytropic retrovirus receptor 1provided by HGNC

Gene Summary: The protein encoded by this gene is a receptor for the xenotropic and polytropic classes of murine leukemia viruses. The encoded protein is involved in phosphate homeostasis by mediating phosphate export from the cell. Defects in this gene have been associated with idiopathic basal ganglia calcification-6. [provided by RefSeq, Jun 2016]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO33448 XPR1 Knockout cell line (HeLa) Human XPR1 1:3~1:6 Negative Online Inquiry
KO33449 XPR1 Knockout cell line (HCT 116) Human XPR1 1:2~1:4 Negative Online Inquiry
KO33450 XPR1 Knockout cell line (HEK293) Human XPR1 1:3~1:6 Negative Online Inquiry
KO33451 XPR1 Knockout cell line (A549) Human XPR1 1:3~1:4 Negative Online Inquiry

Background

XPR1 Gene Knockout Cell Lines are genetically engineered cell lines in which the XPR1 gene has been selectively inactivated, allowing for in-depth studies of its biological functions and interactions. The XPR1 gene encodes the XPR1 protein, a known receptor and transporter involved in the regulation of various signaling pathways, particularly those related to phosphate and viral infection mechanisms. By utilizing CRISPR-Cas9 technology or other advanced gene-editing tools, these cell lines enable researchers to efficiently study the effects of XPR1 gene disruption on cellular processes, including proliferation, differentiation, and response to pathogens.

The key functionality of XPR1 Gene Knockout Cell Lines lies in their ability to represent a controlled environment for examining the role of XPR1 in both physiological and pathological contexts. By studying these knockout models, scientists can elucidate the mechanisms underlying conditions such as viral infections, phosphate metabolism disorders, and potentially oncogenic processes. This has profound implications for both basic research and clinical applications, particularly in developing therapeutic strategies targeting XPR1-associated diseases.

Compared to traditional methods of gene silencing, such as RNA interference, XPR1 Gene Knockout Cell Lines offer greater specificity and permanence in gene inactivation, making them invaluable tools for scientists aiming to achieve precise genetic modifications for longitudinal studies. Additionally, these knockout cell lines often exhibit a more consistent and reproducible response, enhancing the reliability of experimental results.

The scientific importance of XPR1 Gene Knockout Cell Lines is underscored by their potential impact on enhancing our understanding of cellular signaling and disease mechanisms, which is vital for developing innovative treatment approaches. For researchers and clinicians, the availability of these cell lines provides a critical advantage in exploratory research and drug development.

Our company specializes in the design and development of cutting-edge genetic tools and models, demonstrating a long-standing commitment to advancing biological and clinical research. We ensure high-quality products backed by robust scientific expertise, aiding the global research community in unlocking the mysteries of gene function and disease.

Please note that all services are for research use only. Not intended for any clinical use.

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