Gene: WNT2B
Official Full Name: Wnt family member 2Bprovided by HGNC
Gene Summary: This gene encodes a member of the wingless-type MMTV integration site (WNT) family of highly conserved, secreted signaling factors. WNT family members function in a variety of developmental processes including regulation of cell growth and differentiation and are characterized by a WNT-core domain. This gene may play a role in human development as well as carcinogenesis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2014]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO11628 | WNT2B Knockout cell line (HCT 116) | Human | WNT2B | 1:2~1:4 | Negative | Online Inquiry |
WNT2B Gene Knockout Cell Lines are genetically engineered cell lines specifically designed to lack the WNT2B gene, an essential component of the Wnt signaling pathway, which plays a vital role in various biological processes such as cell proliferation, differentiation, and tissue homeostasis. By generating WNT2B knockout models, researchers have a powerful tool to study the gene's functional role in development, cancer progression, and other pathophysiological conditions.
These cell lines function by utilizing CRISPR-Cas9 technology to precisely target and disrupt the WNT2B gene, thereby allowing for the investigation of downstream effects and the involvement of this gene in signaling cascades. Through the knockout model, scientists can elucidate the implications of WNT2B loss on cell behavior, gene expression profiles, and metabolic pathways, contributing significantly to the understanding of how dysregulation of this pathway can lead to disease.
In both research and clinical settings, WNT2B Gene Knockout Cell Lines serve as invaluable tools in cancer biology, regenerative medicine, and developmental studies. They provide insights that are critical for developing targeted therapies and understanding the molecular underpinnings of diseases linked to Wnt signaling aberrations.
Compared to alternative cell lines that may retain functional WNT2B, these knockout lines offer a more straightforward and definitive approach to study the consequences of WNT2B deficiency. This specificity helps to minimize confounding variables, thus ensuring more reliable and reproducible results.
For researchers and clinicians alike, adopting WNT2B Gene Knockout Cell Lines represents an opportunity to push the boundaries of current scientific knowledge. The ability to perform targeted investigations into the role of WNT2B can accelerate therapeutic advancements and lead to improved patient outcomes.
Our company prides itself on delivering high-quality, precision-engineered biological products that support innovative research across various disciplines. With a commitment to scientific excellence and customer success, we provide researchers and clinicians with the tools needed to advance their studies and ultimately impact human health positively.
Please note that all services are for research use only. Not intended for any clinical use.
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