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WDFY1 Knockout Cell Lines

Gene: WDFY1

Official Full Name: WD repeat and FYVE domain containing 1provided by HGNC

Gene Summary: The protein encoded by this gene is a phosphatidylinositol 3-phosphate binding protein, which contains a FYVE zinc finger domain and multiple WD-40 repeat domains. When exogenously expressed, it localizes to early endosomes. Mutagenesis analysis demonstrates that this endosomal localization is mediated by the FYVE domain. [provided by RefSeq, Jan 2015]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO12622 WDFY1 Knockout cell line (HeLa) Human WDFY1 1:3~1:6 Negative Online Inquiry
KO12623 WDFY1 Knockout cell line (HCT 116) Human WDFY1 1:2~1:4 Negative Online Inquiry
KO12624 WDFY1 Knockout cell line (HEK293) Human WDFY1 1:3~1:6 Negative Online Inquiry
KO12625 WDFY1 Knockout cell line (A549) Human WDFY1 1:3~1:4 Negative Online Inquiry

Background

WDFY1 Gene Knockout Cell Lines are genetically engineered cell models designed to facilitate the study of the WDFY1 gene's role in various biological processes and disease states. These cell lines are created through CRISPR-Cas9 technology, allowing for precise deletion of the WDFY1 gene, which codes for a protein involved in cell signaling and autophagy regulation. By disrupting this gene, researchers can investigate the downstream impacts on cellular function and the potential mechanisms underlying conditions such as neurodegenerative diseases and cancer.

The key function of WDFY1 lies in its involvement in endosomal trafficking and autophagy, processes essential for maintaining cellular homeostasis. The knockout of WDFY1 leads to significant alterations in lipid metabolism, protein turnover, and cellular response to stress. Through these cell lines, scientists can elucidate the molecular cascades affected by the absence of WDFY1, providing insights into its biological significance.

Scientifically, these cell lines hold great importance in both research and clinical settings. They serve as vital tools for drug discovery, allowing for high-throughput screening of therapeutic compounds that may influence autophagy or modify the pathological outcomes observed in WDFY1-related disorders. Additionally, they can enhance the understanding of gene-environment interactions that drive cellular dysregulation.

What sets our WDFY1 Gene Knockout Cell Lines apart from alternative products is their validated performance and rigorous quality control measures. Unlike standard cell lines, which may carry multiple genetic variations, our knockout models ensure precise genetic modifications that reflect true functional loss of WDFY1. This specificity translates into more reliable experimental outcomes, empowering researchers and clinicians to obtain meaningful data.

The value of the WDFY1 Gene Knockout Cell Lines lies in their ability to bridge basic research and clinical applications. Researchers can leverage these models to explore novel therapeutic pathways, while clinicians can utilize them to understand patient-specific responses in the context of WDFY1-related diseases.

Our company prides itself on its commitment to excellence in biological product development, backed by a team of experts in genetic engineering and molecular biology. By offering high-quality gene knockout models, we empower the scientific community with the tools needed to advance knowledge in the field of cell biology and translational medicine.

Please note that all services are for research use only. Not intended for any clinical use.

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