Gene: Vtcn1
Official Full Name: V-set domain containing T cell activation inhibitor 1provided by MGI
Gene Summary: Enables signaling receptor binding activity. Acts upstream of or within positive regulation of interleukin-2 production; regulation of T cell activation; and response to protozoan. Located in external side of plasma membrane. Is expressed in several structures, including hemolymphoid system gland; liver; lung; male reproductive gland or organ; and pancreas. Orthologous to human VTCN1 (V-set domain containing T cell activation inhibitor 1). [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO01155 | Vtcn1 Knockout cell line (B16-F10) | Mouse | Vtcn1 | 1:3~1:4 | Negative | Online Inquiry |
Vtcn1 Gene Knockout Cell Lines are specialized cellular models wherein the Vtcn1 gene has been completely inactivated, enabling researchers to study the function of this gene and its role in various biological processes. Knockout cell lines serve as precise tools to elucidate gene functions and the implications of gene loss in pathophysiological contexts. This particular gene is known for its involvement in immune regulation and may play critical roles in both innate and adaptive immune responses, making it an area of interest in cancer research and immunotherapy.
Mechanistically, the Vtcn1 gene encodes a protein that modulates the activity of immune cells; thus, by knocking out this gene, researchers can observe changes in cell signaling pathways, cytokine production, and overall cellular behavior. Such studies are pivotal as they can reveal insights into immune evasion mechanisms of tumors and the modulation of immune responses in chronic infections.
The scientific importance of Vtcn1 Gene Knockout Cell Lines is multifaceted. In research settings, these models can be employed to investigate the effects of Vtcn1 loss in various disease models, facilitating the identification of novel therapeutic targets. Clinically, findings derived from studies using these knockout lines can inform the development of specific immunotherapies that enhance anti-tumor immunity or combat autoimmune diseases.
Compared to alternative models, such as non-targeted knockouts or wild-type controls, Vtcn1 Gene Knockout Cell Lines provide researchers with a targeted approach to studying gene functions, thereby yielding more reliable and reproducible results. The specific deficiency of the Vtcn1 gene facilitates detailed mechanistic studies that are often obscured in heterogeneous populations of cells.
Invaluable for both researchers and clinicians, these knockout cell lines enhance the understanding of complex biological processes, ultimately driving innovations in treatment strategies. Our company brings forth a wealth of expertise in genetic modification technologies, ensuring that our Vtcn1 Gene Knockout Cell Lines are produced with rigor and precision, meeting the highest standards for scientific inquiry and application.
Please note that all services are for research use only. Not intended for any clinical use.
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