Home / VSX1 Knockout Cell Lines

VSX1 Knockout Cell Lines

Gene: VSX1

Official Full Name: visual system homeobox 1provided by HGNC

Gene Summary: The protein encoded by this gene contains a paired-like homeodomain and binds to the core of the locus control region of the red/green visual pigment gene cluster. The encoded protein may regulate expression of the cone opsin genes early in development. Mutations in this gene can cause posterior polymorphous corneal dystrophy and keratoconus. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jul 2008]

Get A Quote
Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO26756 VSX1 Knockout cell line (A549) Human VSX1 1:3~1:4 Negative Online Inquiry

Background

VSX1 Gene Knockout Cell Lines are specially engineered cellular models designed to facilitate the study of the VSX1 gene, which encodes a transcription factor involved in various ocular processes. By employing CRISPR-Cas9 gene editing techniques, these cell lines have been meticulously crafted to exhibit a complete disruption of the VSX1 gene, enabling researchers to assess its role in physiological and pathological states, particularly in relation to retinal functions and diseases such as keratoconus.

The primary function of VSX1 Gene Knockout Cell Lines hinges on their ability to mimic gene loss-of-function scenarios. This feature is crucial for dissecting the molecular and cellular pathways influenced by the VSX1 gene. Researchers can observe phenotypic alterations and analyze gene expression changes in response to external stimuli, providing insights into the pathogenic mechanisms underlying visual impairments. Additionally, these knockout lines serve as a platform for the screening of potential therapeutic agents aimed at ameliorating VSX1-related diseases.

The scientific importance of these cell lines cannot be overstated; they play a pivotal role in advancing our understanding of gene functions within ocular biology. In clinical research, they facilitate the discovery of novel biomarkers and therapeutic targets by enabling the elucidation of disease mechanisms, which can lead to innovative treatment strategies for conditions linked to VSX1 dysfunction.

VSX1 Gene Knockout Cell Lines offer several advantages over traditional models, such as primary cells or less specific knockdown systems. The precision of CRISPR editing ensures a robust and reproducible knockout, which is essential for generating reliable data. Moreover, researchers benefit from the consistent genetic background of these cell lines, enhancing experimental translatability.

In summary, VSX1 Gene Knockout Cell Lines are an invaluable resource for researchers and clinicians interested in ocular health. Their unique capabilities facilitate groundbreaking insights into genetic diseases, making them essential tools for advancing biomedical research. Our company is dedicated to providing high-quality biological products and cutting-edge solutions to empower scientific discovery, reflecting our commitment to supporting the research community with the best innovative tools available.

Please note that all services are for research use only. Not intended for any clinical use.

Get a free quote

If your question is not addressed through these resources, you can fill out the online form below and we will answer your question as soon as possible.

0

There is no product in your cart.