Gene: VSIR
Official Full Name: V-set immunoregulatory receptorprovided by HGNC
Gene Summary: Enables endopeptidase activator activity; enzyme binding activity; and identical protein binding activity. Involved in several processes, including negative regulation of cytokine production; positive regulation of metabolic process; and regulation of T cell activation. Located in plasma membrane. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO01318 | VSIR Knockout cell line (A549) | Human | VSIR | 1:3~1:4 | Negative | Online Inquiry |
KO12639 | VSIR Knockout cell line (HeLa) | Human | VSIR | 1:3~1:6 | Negative | Online Inquiry |
KO12640 | VSIR Knockout cell line (HCT 116) | Human | VSIR | 1:2~1:4 | Negative | Online Inquiry |
VSIR Gene Knockout Cell Lines comprise a powerful tool for researchers dedicated to studying gene functions and underlying biological processes. These cell lines are engineered to exhibit a complete deletion of the VSIR gene, which encodes V-domain Ig suppressor of T cell activation and plays a significant role in immune regulation. By facilitating a precise knockout of this gene, researchers can gain deeper insights into its involvement in cellular mechanisms, including T cell modulation and the overall immune response.
The unique mechanism underlying the VSIR Gene Knockout Cell Lines involves advanced genome editing technologies, such as CRISPR-Cas9, allowing for targeted modifications at the genomic level. This specificity not only reduces off-target effects commonly associated with traditional genetic manipulation methods but also enhances the reliability of experimental results. By utilizing these knockout cell lines, researchers can elucidate the role of VSIR in various physiological contexts, including cancer immunotherapy and autoimmune disease research, providing a robust model for experimental validation.
From a scientific perspective, the importance of VSIR Gene Knockout Cell Lines is profound. Their application extends to both basic research and translational studies, offering insights that may drive the development of innovative therapeutic strategies. Compared to conventional methods for gene knockdown, such as RNA interference, these cell lines provide a stable and permanent alteration, allowing for the exploration of long-term effects of gene deletion.
One of the primary advantages of our VSIR Gene Knockout Cell Lines is their unparalleled specificity and robustness, ensuring accurate modeling of VSIR's biological roles. Coupled with a user-friendly protocol for culturing and utilizing these cell lines, researchers can expedite their experiments while reducing variability.
For researchers, clinicians, and pharmaceutical developers, the ability to dissect complex biological pathways and tackle challenging questions around immune system behavior holds immense value. Our commitment to providing high-quality, ready-to-use biological products reflects our understanding of the diverse needs within scientific communities.
At [Your Company Name], we leverage cutting-edge technologies and deep sector expertise to develop advanced cellular models, ensuring that your research is firmly grounded in scientific rigor and innovation. Our VSIR Gene Knockout Cell Lines stand as a testament to our dedication to supporting discovery and advancement in biological research.
Please note that all services are for research use only. Not intended for any clinical use.
If your question is not addressed through these resources, you can fill out the online form below and we will answer your question as soon as possible.
There is no product in your cart. |
CD Biosynsis is a leading customer-focused biotechnology company dedicated to providing high-quality products, comprehensive service packages, and tailored solutions to support and facilitate the applications of synthetic biology in a wide range of areas.