Home / VILL Knockout Cell Lines

VILL Knockout Cell Lines

Gene: VILL

Official Full Name: villin likeprovided by HGNC

Gene Summary: The protein encoded by this gene belongs to the villin/gelsolin family. It contains 6 gelsolin-like repeats and a headpiece domain. It may play a role in actin-bundling. [provided by RefSeq, Jul 2008]

Get A Quote
Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO23274 VILL Knockout cell line (HCT 116) Human VILL 1:2~1:4 Negative Online Inquiry

Background

VILL Gene Knockout Cell Lines are genetically engineered cellular models created to specifically knock out the VILL gene, which plays a crucial role in diverse biological processes including cellular adhesion and signaling pathways. These cell lines are derived from well-characterized parental cell lines through the use of CRISPR-Cas9 technology, which allows for precise genome editing. By eliminating the expression of the VILL gene, these cell lines facilitate the study of its functional role and the consequences of its absence in various cellular contexts.

The primary mechanism underlying these knockouts involves the introduction of double-strand breaks at specific loci of the VILL gene, followed by the introduction of insertions or deletions that disrupt gene function. This leads to significant alterations in cell behavior, making these models indispensable for dissecting the biological pathways associated with VILL. In research and clinical settings, VILL Gene Knockout Cell Lines enable scientists to explore the gene's implications in conditions such as cancer metastasis, developmental biology, and neurobiology, where aberrant adhesion and signaling patterns are often implicated.

Compared to traditional knockout methods, VILL Gene Knockout Cell Lines offer enhanced specificity and efficiency, reducing off-target effects and allowing for more reliable experimental results. Their consistent and reproducible genetic alteration positions these cell lines as a preferred choice for both in vitro and in vivo studies. Researchers and clinicians can significantly benefit from employing these models, gaining insights that could pave the way for future therapies and translational applications.

The value of VILL Gene Knockout Cell Lines lies in their ability to provide researchers with crucial data concerning gene function, disease mechanisms, and potential therapeutic targets. Our commitment to delivering cutting-edge biological products reflects our expertise and dedication to advancing scientific inquiry. As a leader in genetic engineering solutions, we aim to empower the research community with innovative tools that support groundbreaking discoveries.

Please note that all services are for research use only. Not intended for any clinical use.

Get a free quote

If your question is not addressed through these resources, you can fill out the online form below and we will answer your question as soon as possible.

0

There is no product in your cart.