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VEPH1 Knockout Cell Lines

Gene: VEPH1

Official Full Name: ventricular zone expressed PH domain containing 1provided by HGNC

Gene Summary: Predicted to enable phosphatidylinositol-5-phosphate binding activity. Involved in negative regulation of SMAD protein signal transduction and negative regulation of transforming growth factor beta receptor signaling pathway. Predicted to be located in endomembrane system. Predicted to be active in plasma membrane. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO12692 VEPH1 Knockout cell line (HeLa) Human VEPH1 1:3~1:6 Negative Online Inquiry
KO12693 VEPH1 Knockout cell line (HCT 116) Human VEPH1 1:2~1:4 Negative Online Inquiry

Background

VEPH1 Gene Knockout Cell Lines are a sophisticated biological tool designed to facilitate comprehensive studies on the VEPH1 gene's functional roles in various cellular processes. These cell lines have been engineered using state-of-the-art CRISPR/Cas9 technology, resulting in specific deletion of the VEPH1 gene. This knockout model is pivotal for researchers aiming to elucidate the gene’s contributions to biological functions such as cell proliferation, differentiation, and response to environmental stressors.

The primary mechanism of action for VEPH1 Gene Knockout Cell Lines lies in their ability to render the VEPH1 protein inactive, thereby allowing scientists to observe the resultant phenotypic changes and biochemical pathways that may be altered in its absence. This enables researchers to dissect the molecular underpinnings of diseases related to dysregulated VEPH1 expression, such as certain cancers or metabolic disorders.

The scientific importance of these cell lines extends to both fundamental research and potential clinical applications. They provide a robust platform for high-throughput drug screening, gene editing validation, and functional genomics. Their use can also facilitate the development of personalized medicine approaches by allowing clinicians to study patient-specific mutations in a controlled environment.

In comparison to alternative models, VEPH1 Gene Knockout Cell Lines offer unparalleled specificity and efficiency, reducing the risk of off-target effects often seen with traditional gene knockouts. Additionally, our cell lines are rigorously validated for consistent performance, ensuring that researchers can obtain reproducible results for their studies.

For researchers and clinicians, the ability to interrogate gene function accurately holds immense value. The insights gained from utilizing VEPH1 Gene Knockout Cell Lines are essential for advancing our understanding of gene functions and their implications in health and disease.

Our company is dedicated to providing high-quality biological products backed by extensive expertise in molecular genetics and cellular biology. We are committed to supporting the scientific community with tools that empower discovery and enhance research capabilities.

Please note that all services are for research use only. Not intended for any clinical use.

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