Gene: USP10
Official Full Name: ubiquitin specific peptidase 10provided by HGNC
Gene Summary: Ubiquitin is a highly conserved protein that is covalently linked to other proteins to regulate their function and degradation. This gene encodes a member of the ubiquitin-specific protease family of cysteine proteases. The enzyme specifically cleaves ubiquitin from ubiquitin-conjugated protein substrates. The protein is found in the nucleus and cytoplasm. It functions as a co-factor of the DNA-bound androgen receptor complex, and is inhibited by a protein in the Ras-GTPase pathway. The human genome contains several pseudogenes similar to this gene. Several transcript variants, some protein-coding and others not protein-coding, have been found for this gene. [provided by RefSeq, Jan 2013]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO00508 | USP10 Knockout cell line (HEK293) | Human | USP10 | 1:3~1:6 | Negative | Online Inquiry |
KO05679 | USP10 Knockout cell line (HeLa) | Human | USP10 | 1:3~1:6 | Negative | Online Inquiry |
KO05680 | USP10 Knockout cell line (HCT 116) | Human | USP10 | 1:2~1:4 | Negative | Online Inquiry |
KO05681 | USP10 Knockout cell line (A549) | Human | USP10 | 1:3~1:4 | Negative | Online Inquiry |
USP10 Gene Knockout Cell Lines are engineered cellular models specifically designed to facilitate the study of the ubiquitin-specific peptidase 10 (USP10) gene, a vital component within cellular pathways related to protein degradation and regulation. These cell lines have undergone comprehensive CRISPR/Cas9 gene editing to create targeted knockouts, thereby providing researchers with an invaluable tool to investigate the biological roles of USP10 and its implications in various physiological and pathophysiological processes.
The primary function of USP10 involves the deubiquitination of target proteins, influencing multiple cellular processes including protein stability, signal transduction, and DNA repair mechanisms. By utilizing these knockout cell lines, scientists can assess how the absence of USP10 affects cellular response to stress, inflammation, and oncogenesis, providing insights into its role in diseases, including cancer and neurodegenerative disorders.
The scientific importance of USP10 Gene Knockout Cell Lines is evidenced by their application in critical research fields such as cancer biology, developmental biology, and pharmacology. They serve as essential platforms for drug screening, validation of therapeutic targets, and understanding the mechanisms of diseases, thus bridging the gap between basic research and clinical applications.
What distinguishes our USP10 Gene Knockout Cell Lines from alternatives is the precision and reliability of the CRISPR/Cas9 technology employed, ensuring high efficiency and specificity in gene editing. Additionally, our cell lines undergo extensive quality control measures, ensuring consistent performance across experiments and enhanced reproducibility of results.
For researchers, clinicians, and other professionals, the value of USP10 Gene Knockout Cell Lines lies in their versatility and potential to accelerate discovery in critical areas of biomedical research. When utilized, these cell lines significantly streamline experimental workflows, leading to more efficient and effective research outcomes.
At our company, we specialize in providing high-quality biological products designed to meet the rigorous demands of modern scientific research. With a commitment to innovation and excellence, we support our customers with expert knowledge and tailored solutions that advance their research goals.
Please note that all services are for research use only. Not intended for any clinical use.
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