Gene: UCA1
Official Full Name: urothelial cancer associated 1provided by HGNC
Gene Summary: This gene produces a long non-coding RNA that was found to be upregulated in bladder cancer and plays a regulatory role in cell proliferation. This transcript regulates several genes, including CREB (cAMP responsive element binding protein). Expression of this transcript is regulated by CCAAT/enhancer-binding protein-alpha. [provided by RefSeq, Dec 2017]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO01439 | UCA1 Knockout cell line(A549/DDP) | Human | UCA1 | 1:3~1:4 | Negative | Online Inquiry |
UCA1 Gene Knockout Cell Lines are genetically engineered cellular models designed to effectively eliminate the expression of the UCA1 gene, allowing researchers to investigate its biological implications in various disease contexts, including cancer and metabolic disorders. This precise knockout technology leverages CRISPR-Cas9 gene editing methods, ensuring accurate deletion of the UCA1 gene, which plays a critical role in cellular processes such as proliferation, differentiation, and apoptosis.
The key function of these cell lines lies in their ability to facilitate functional studies, providing researchers with the capacity to closely monitor the phenotypic changes that occur in the absence of UCA1. Through the manipulation of this gene, researchers can uncover insights into its regulatory networks and identify potential therapeutic targets. Moreover, UCA1 has been implicated in the development and progression of several malignancies, making these knockout cell lines invaluable for preclinical studies aimed at developing novel cancer therapies.
One of the standout advantages of UCA1 Gene Knockout Cell Lines is their specificity and reproducibility, which surpasses traditional knockdown methods like siRNA or shRNA, often resulting in off-target effects. Additionally, these knockout models offer a more stable genetic alteration, ensuring consistent results across experiments. By using these specialized cell lines, researchers and clinicians can confidently explore the UCA1 gene’s role in pathophysiology or therapeutic response, paving the way for innovative strategies in disease management.
In summary, UCA1 Gene Knockout Cell Lines provide a cutting-edge tool for exploring gene function and disease mechanisms, making them essential for researchers and clinicians alike. Our company, recognized for its commitment to advancing biomedical research through high-quality biological products, stands ready to support your investigations with these expertly developed cell lines, ensuring that you have the best resources to drive scientific discovery.
Please note that all services are for research use only. Not intended for any clinical use.
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