Gene: U2AF1L4
Official Full Name: U2 small nuclear RNA auxiliary factor 1 like 4provided by HGNC
Gene Summary: Predicted to enable pre-mRNA 3'-splice site binding activity. Predicted to be involved in mRNA splicing, via spliceosome. Predicted to be located in nucleoplasm. Predicted to be part of U2AF complex and spliceosomal complex. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO21288 | U2AF1L4 Knockout cell line (HeLa) | Human | U2AF1L4 | 1:3~1:6 | Negative | Online Inquiry |
KO21289 | U2AF1L4 Knockout cell line (HCT 116) | Human | U2AF1L4 | 1:2~1:4 | Negative | Online Inquiry |
KO21290 | U2AF1L4 Knockout cell line (HEK293) | Human | U2AF1L4 | 1:3~1:6 | Negative | Online Inquiry |
KO21291 | U2AF1L4 Knockout cell line (A549) | Human | U2AF1L4 | 1:3~1:4 | Negative | Online Inquiry |
U2AF1L4 Gene Knockout Cell Lines are genetically modified cellular systems developed using advanced CRISPR-Cas9 technology to facilitate precise disruption of the U2AF1L4 gene. These cell lines serve as invaluable tools for researchers investigating the role of U2AF1L4 in various biological processes, particularly its involvement in mRNA splicing and regulatory pathways. By creating these knockout models, scientists can observe the phenotypic effects and molecular alterations that result from the absence of U2AF1L4, thus gaining insights into its function within the genome.
The key mechanism of these cell lines lies in their ability to provide a simplified model for studying loss-of-function mutations. When the U2AF1L4 gene is knocked out, researchers can monitor changes at the mRNA and protein levels, enabling a deeper understanding of its contribution to cellular physiology. This is particularly crucial for studies focusing on disorders associated with splicing abnormalities, including certain cancers and genetic diseases. The applications of U2AF1L4 knockout cell lines extend beyond basic research; they hold potential for developing targeted therapies and for drug screening processes.
What sets our U2AF1L4 Gene Knockout Cell Lines apart from other genetic models is the precision and reliability afforded by our rigorous quality control measures during cell line development. Each line is validated through extensive sequencing and expression analysis to confirm the knockout's efficacy, ensuring researchers obtain reproducible and high-quality results. The ease of use and compatibility with standard laboratory protocols further enhance their appeal.
Researchers and clinicians can benefit significantly from incorporating U2AF1L4 Gene Knockout Cell Lines into their studies, as they not only facilitate groundbreaking discoveries but also streamline experimental workflows. This product is essential for advancing knowledge in gene function and therapeutic target validation, making it a critical asset for any laboratory focused on genetic and cellular research.
Our company prides itself on its commitment to high-quality biological products backed by extensive expertise in gene editing technologies. We strive to support the scientific community with reliable tools that enable exploration and innovation in genetics and cellular biology.
Please note that all services are for research use only. Not intended for any clinical use.
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