Gene: TTLL11
Official Full Name: tubulin tyrosine ligase like 11provided by HGNC
Gene Summary: Predicted to enable tubulin binding activity and tubulin-glutamic acid ligase activity. Predicted to be involved in microtubule cytoskeleton organization. Predicted to act upstream of or within microtubule severing and protein polyglutamylation. Predicted to be located in cytosol. Predicted to be active in ciliary basal body. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO12942 | TTLL11 Knockout cell line (HeLa) | Human | TTLL11 | 1:3~1:6 | Negative | Online Inquiry |
KO12943 | TTLL11 Knockout cell line (HCT 116) | Human | TTLL11 | 1:2~1:4 | Negative | Online Inquiry |
KO12944 | TTLL11 Knockout cell line (HEK293) | Human | TTLL11 | 1:3~1:6 | Negative | Online Inquiry |
KO12945 | TTLL11 Knockout cell line (A549) | Human | TTLL11 | 1:3~1:4 | Negative | Online Inquiry |
TTLL11 Gene Knockout Cell Lines are genetically engineered cell models that have had the TTLL11 gene inactivated to provide researchers with a powerful tool for studying the gene's function and its role in various biological processes. The TTLL11 gene encodes a protein that is involved in the post-translational modification of tubulin, a key component of the cytoskeleton. By knocking out this gene, these cell lines allow scientists to investigate the impacts of altered tubulin dynamics on cellular pathways, thus elucidating mechanisms that could be involved in disease progression, particularly in neurodegenerative disorders.
The key functionalities of the TTLL11 Gene Knockout Cell Lines include enabling researchers to assess changes in microtubule stability, cellular morphology, and signaling pathways. With the loss of the TTLL11 protein, researchers can examine the resultant biochemical and phenotypic shifts in the cell lines, helping to clarify the role of tubulin modifications in cell division, intracellular transport, and overall cell health. Such cellular models are invaluable in dissecting gene functions, drug responses, and the mechanisms of pathological conditions, making them vital in both basic and applied research settings.
The scientific importance of these cell lines cannot be overstated, as they offer an innovative way to study the implications of tubulin modification at the molecular level. In clinical contexts, they pave the way for understanding complex diseases where aberrations in the cytoskeleton are implicated, potentially guiding therapeutic discoveries. Compared to other gene knockout models, the TTLL11 lines provide a specific focus on tubulin-related studies, which is often overlooked yet critical in a myriad of conditions.
One major advantage of the TTLL11 Gene Knockout Cell Lines is their versatility; they can be easily integrated into a variety of experimental setups, including drug screening, genetic interaction analyses, and systems biology approaches. This feature, combined with a thorough characterization of the knockout, positions these cell lines as superior tools for researchers looking to derive meaningful insights from their experiments.
For researchers and clinicians dedicated to exploring the frontiers of cellular biology and disease mechanisms, the TTLL11 Gene Knockout Cell Lines represent a significant value-add. They not only support robust experimental designs but also contribute to advancing the understanding of critical cellular functions. With our company’s strong commitment to providing high-quality biological products backed by extensive research and development, we ensure that our offerings, including these knockout cell lines, meet the rigorous demands of contemporary biological research.
Please note that all services are for research use only. Not intended for any clinical use.
If your question is not addressed through these resources, you can fill out the online form below and we will answer your question as soon as possible.
There is no product in your cart. |
CD Biosynsis is a leading customer-focused biotechnology company dedicated to providing high-quality products, comprehensive service packages, and tailored solutions to support and facilitate the applications of synthetic biology in a wide range of areas.