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TTC7B Knockout Cell Lines

Gene: TTC7B

Official Full Name: tetratricopeptide repeat domain 7Bprovided by HGNC

Gene Summary: Involved in phosphatidylinositol phosphate biosynthetic process and protein localization to plasma membrane. Located in cytosol and plasma membrane. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO24043 TTC7B Knockout cell line (HeLa) Human TTC7B 1:3~1:6 Negative Online Inquiry
KO24044 TTC7B Knockout cell line (HCT 116) Human TTC7B 1:2~1:4 Negative Online Inquiry
KO24045 TTC7B Knockout cell line (HEK293) Human TTC7B 1:3~1:6 Negative Online Inquiry
KO24046 TTC7B Knockout cell line (A549) Human TTC7B 1:3~1:4 Negative Online Inquiry

Background

TTC7B Gene Knockout Cell Lines are specialized, genetically modified cell lines created to study the functional consequences of the loss of the TTC7B gene, which is implicated in various biological processes, including immune system function and cellular signaling pathways. These cell lines are invaluable tools for researchers seeking to elucidate the specific roles of TTC7B in health and disease, particularly in the context of immunodeficiencies and related disorders.

The mechanism behind the functionality of these knockout cell lines stems from the precise genetic editing techniques, such as CRISPR/Cas9, employed to ablate the TTC7B gene. By generating these cell lines, scientists can observe the phenotypic consequences of gene knockout, evaluating changes in proliferation, signaling cascades, and responses to stimuli. This aids in the understanding of the protein's role as a scaffold in the assembly of signaling complexes crucial for immune response.

The scientific importance of TTC7B Gene Knockout Cell Lines is underscored by their applications in both fundamental research and potential clinical applications. They enable the investigation of disease mechanisms at a cellular level and facilitate the development of targeted therapies aimed at restoring immune function. Additionally, they serve as platforms for testing the efficacy of new drugs that might modulate TTC7B-related pathways.

What distinguishes our TTC7B Gene Knockout Cell Lines from alternatives is their high specificity, validated performance, and the robust consistency of results across experimental conditions. Researchers can rely on these cell lines to produce reproducible data, crucial for advancing understanding in complex systems where gene function may be implicated.

For researchers and clinicians aiming to probe the intricacies of gene function and its implications in disease, TTC7B Gene Knockout Cell Lines represent a vital asset. By choosing our product, you are investing in high-quality, rigorously validated models that can significantly enhance your research outcomes.

Our company prides itself on its commitment to excellence in genetic engineering and cell line development, leveraging extensive expertise to provide researchers with the highest quality biological products that drive innovation in life sciences.

Please note that all services are for research use only. Not intended for any clinical use.

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