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TTC7A Knockout Cell Lines

Gene: TTC7A

Official Full Name: tetratricopeptide repeat domain 7Aprovided by HGNC

Gene Summary: This gene encodes a protein containing tetratricopeptide repeats. Mutations in this gene disrupt intestinal development and can cause early onset inflammatory bowel disease and intestinal atresia. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2014]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO02114 TTC7A Knockout cell line (HeLa) Human TTC7A 1:3~1:6 Negative Online Inquiry
KO02115 TTC7A Knockout cell line (HCT 116) Human TTC7A 1:2~1:4 Negative Online Inquiry
KO02116 TTC7A Knockout cell line (HEK293) Human TTC7A 1:3~1:6 Negative Online Inquiry
KO02117 TTC7A Knockout cell line (A549) Human TTC7A 1:3~1:4 Negative Online Inquiry

Background

TTC7A Gene Knockout Cell Lines are a specialized cellular model system that have been engineered to lack the TTC7A gene, which encodes a critical protein involved in multiple cellular functions, including signal transduction, cellular differentiation, and immune response regulation. This knockout approach allows researchers to dissect the biological roles of TTC7A in health and disease, offering powerful insights into various molecular pathways.

The key functions of these cell lines revolve around their application in studying gene function and elucidating mechanisms that are altered in TTC7A-related disorders. By creating a defined cellular context where the TTC7A gene is absent, scientists can observe resulting physiological changes, dysregulation of signaling pathways, and variations in cellular behavior. This enables comprehensive analyses such as high-throughput drug screening, functional genomics, and mechanistic studies relevant to immune system functioning and various diseases, including inflammatory disorders and immunodeficiencies.

The scientific importance of TTC7A Gene Knockout Cell Lines is underscored by their utility in both research and clinical settings, paving the way for targeted therapeutic approaches and novel treatment strategies. By investigating the roles of specific genes in disease etiology, they enable identification of potential biomarkers and drug targets that can lead to more effective personalized medicine.

What sets our TTC7A Gene Knockout Cell Lines apart is their high specificity and reliability, backed by rigorous validation processes that ensure reproducibility and accurate representation of the loss-of-function phenotype. Unlike alternative models, these cell lines offer a unique platform for in-depth investigations, reducing variability and enhancing the quality of experimental outcomes.

Researchers and clinicians seeking to advance their understanding of gene functions, disease mechanisms, and therapeutic interventions will find immense value in our TTC7A Gene Knockout Cell Lines. They not only facilitate cutting-edge research but also align with comprehensive study designs in various experimental applications.

Our company prides itself on a commitment to excellence in the production of biological products, leveraging state-of-the-art technology and profound expertise in genetic engineering to support scientific innovation and drive progress in life sciences research.

Please note that all services are for research use only. Not intended for any clinical use.

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