Gene: TTC23
Official Full Name: tetratricopeptide repeat domain 23provided by HGNC
Gene Summary: Predicted to be involved in positive regulation of smoothened signaling pathway. Predicted to be located in cilium. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO12959 | TTC23 Knockout cell line (HeLa) | Human | TTC23 | 1:3~1:6 | Negative | Online Inquiry |
KO12960 | TTC23 Knockout cell line (HCT 116) | Human | TTC23 | 1:2~1:4 | Negative | Online Inquiry |
KO12961 | TTC23 Knockout cell line (HEK293) | Human | TTC23 | 1:3~1:6 | Negative | Online Inquiry |
KO12962 | TTC23 Knockout cell line (A549) | Human | TTC23 | 1:3~1:4 | Negative | Online Inquiry |
TTC23 Gene Knockout Cell Lines are specialized biological tools designed to facilitate the functional analysis of the TTC23 gene. These cell lines have been meticulously engineered to exhibit a complete knockout of the TTC23 gene, providing researchers with a unique platform to study gene function, regulation, and the biological pathways influenced by this gene. The rigorous techniques employed in creating these knockout lines ensure that the resulting cellular models are stable and reproducible, offering consistency across experiments.
The primary mechanism of action involves CRISPR/Cas9 gene-editing technology, which employs targeted double-strand breaks in the TTC23 gene, resulting in insertion or deletion mutations that effectively disrupt the gene’s coding sequence. This knockout feature enables researchers to observe phenotypic changes and alterations in cellular processes, including proliferation, differentiation, and response to external stimuli. These insights are crucial for understanding the role of TTC23 in various biological contexts, including developmental biology and disease mechanisms.
The scientific importance of TTC23 Gene Knockout Cell Lines extends to both fundamental research and clinical applications. For instance, they can be invaluable in the investigation of diseases where TTC23 might play a role, such as in neurodegenerative disorders or cancers, allowing for the identification of potential therapeutic targets. Furthermore, these cell lines can be utilized in drug screening processes, aiding in the discovery of new pharmacological agents.
One of the significant advantages of our TTC23 Gene Knockout Cell Lines is their specificity and reliability compared to alternative research models, such as whole organism studies or transient knockdown systems. The permanence of the knockout allows for long-term studies, resulting in better reproducibility of results. Additionally, these cell lines come with thorough characterization data and quality control assessments, ensuring users can trust their experimental outcomes.
With our extensive expertise in the generation and optimization of gene-editing cell lines, we are committed to supporting the scientific community in tackling complex biological questions. Our TTC23 Gene Knockout Cell Lines stand as a testament to our dedication to providing high-quality, innovative research tools that empower researchers and clinicians alike to advance their work effectively.
Please note that all services are for research use only. Not intended for any clinical use.
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