Gene: TSPAN6
Official Full Name: tetraspanin 6provided by HGNC
Gene Summary: The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. The protein encoded by this gene is a cell surface glycoprotein and is highly similar in sequence to the transmembrane 4 superfamily member 2 protein. It functions as a negative regulator of retinoic acid-inducible gene I-like receptor-mediated immune signaling via its interaction with the mitochondrial antiviral signaling-centered signalosome. This gene uses alternative polyadenylation sites, and multiple transcript variants result from alternative splicing. [provided by RefSeq, Jul 2013]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO34990 | TSPAN6 Knockout cell line (HeLa) | Human | TSPAN6 | 1:3~1:6 | Negative | Online Inquiry |
KO34991 | TSPAN6 Knockout cell line (HCT 116) | Human | TSPAN6 | 1:2~1:4 | Negative | Online Inquiry |
KO34992 | TSPAN6 Knockout cell line (HEK293) | Human | TSPAN6 | 1:3~1:6 | Negative | Online Inquiry |
KO34993 | TSPAN6 Knockout cell line (A549) | Human | TSPAN6 | 1:3~1:4 | Negative | Online Inquiry |
TSPAN6 Gene Knockout Cell Lines are genetically modified cellular systems specifically designed to facilitate the study of the tetraspanin 6 (TSPAN6) gene's functions and its implications in cellular processes. These cell lines are engineered using advanced CRISPR/Cas9 technology to create reliable models that lack the TSPAN6 gene. This knockout allows researchers to investigate the resultant phenotypic changes, offering insights into TSPAN6's role in various cellular functions, including cellular signaling, adhesion, and migration.
The primary function of these knockout cell lines rests in their ability to provide a controlled environment for the examination of TSPAN6-related pathways. By elucidating the biological roles of TSPAN6, researchers can uncover its relationships with other genes and proteins, thereby contributing to a more comprehensive understanding of its involvement in health and disease, particularly in cancer progression and immune response regulation.
In scientific and clinical research settings, the TSPAN6 Gene Knockout Cell Lines serve as invaluable tools for drug discovery and biomarker identification, ultimately enhancing the development of targeted therapies. They enable researchers to determine the potential therapeutic efficacy and specificity of novel candidates against TSPAN6-associated conditions, paving the way for more personalized medicine.
One of the unique advantages of our TSPAN6 Gene Knockout Cell Lines lies in our rigorous validation process and commitment to ensuring reproducibility. Compared to other less-optimized genetic models available in the market, our products come with detailed characterization data and a consistent performance record in various applications, such as high-throughput screening and functional assays.
Selecting TSPAN6 Gene Knockout Cell Lines from our company means leveraging cutting-edge technology backed by a dedicated team of experts in genetic engineering and cell biology. We pride ourselves on delivering top-quality biological products that empower researchers to advance their investigations, offering not just the tools needed for discovery but also the scientific support necessary for innovation.
Please note that all services are for research use only. Not intended for any clinical use.
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