Gene: TSHZ1
Official Full Name: teashirt zinc finger homeobox 1provided by HGNC
Gene Summary: This gene encodes a colon cancer antigen that was defined by serological analysis of recombinant cDNA expression libraries. The encoded protein is a member of the teashirt C2H2-type zinc-finger protein family and may be involved in transcriptional regulation of developmental processes. Mutations in this gene may be associated with congenital aural atresia syndrome. [provided by RefSeq, Jan 2012]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO32174 | TSHZ1 Knockout cell line (HeLa) | Human | TSHZ1 | 1:3~1:6 | Negative | Online Inquiry |
KO32175 | TSHZ1 Knockout cell line (HCT 116) | Human | TSHZ1 | 1:2~1:4 | Negative | Online Inquiry |
KO32176 | TSHZ1 Knockout cell line (HEK293) | Human | TSHZ1 | 1:3~1:6 | Negative | Online Inquiry |
KO32177 | TSHZ1 Knockout cell line (A549) | Human | TSHZ1 | 1:3~1:4 | Negative | Online Inquiry |
TSHZ1 Gene Knockout Cell Lines are specialized cellular models engineered to disrupt the expression of the TSHZ1 gene, which is implicated in various biological processes including neurodevelopment, cell signaling, and tissue differentiation. These cell lines are typically generated using CRISPR/Cas9 technology, allowing for precise, efficient edits in the genome that lead to modified functions and phenotypes. By impairing the TSHZ1 gene, researchers can effectively investigate its role in cellular behavior and disease mechanisms.
The primary function of the TSHZ1 gene is linked to transcriptional regulation, and its knockout leads to profound effects on gene expression profiles critical for neuronal function. Utilizing these knockout cell lines enables scientists to explore fundamental questions concerning neurogenesis, synaptic plasticity, and potential contributions to neurological disorders such as autism and schizophrenia. Furthermore, these cell lines serve as powerful tools to screen for new pharmacological agents or understand responses to environmental factors affecting TSHZ1 activity.
The scientific significance of TSHZ1 Gene Knockout Cell Lines lies in their ability to provide a model for elucidating the intricacies of gene function in health and disease. Compared to traditional knockout models, these cell lines offer a more accessible and versatile platform for high-throughput screening and innovative experimental designs. Their rapid adaptability to various assays, including drug response evaluations and gene expression studies, sets them apart from other models, which may require extensive animal experimentation.
For researchers and clinicians aiming to bridge the gap between molecular biology and therapeutic interventions, TSHZ1 Gene Knockout Cell Lines present unparalleled opportunities to advance understanding and inform treatment strategies. By providing a reliable and relevant model to dissect the functional aspects of TSHZ1, users can accelerate their research outcomes and contribute significantly to the field of genetics and translational medicine.
At our company, we pride ourselves on our commitment to developing state-of-the-art biological products, meticulously designed to meet the evolving needs of the research community. Our expertise in gene editing technologies ensures that our TSHZ1 Gene Knockout Cell Lines are of the highest quality and rigor, helping to empower scientists to push the boundaries of discovery.
Please note that all services are for research use only. Not intended for any clinical use.
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