Gene: TRUB1
Official Full Name: TruB pseudouridine synthase family member 1provided by HGNC
Gene Summary: Pseudouridine is an abundant component of rRNAs and tRNAs and is enzymatically generated by isomerization of uridine by pseudouridine synthase (Zucchini et al., 2003 [PubMed 12736709]).[supplied by OMIM, Mar 2008]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO01365 | TRUB1 Knockout cell line (HeLa) | Human | TRUB1 | 1:3~1:6 | Negative | Online Inquiry |
KO01879 | TRUB1 Knockout cell line (HCT 116) | Human | TRUB1 | 1:2~1:4 | Negative | Online Inquiry |
KO01880 | TRUB1 Knockout cell line (HEK293) | Human | TRUB1 | 1:3~1:6 | Negative | Online Inquiry |
KO01881 | TRUB1 Knockout cell line (A549) | Human | TRUB1 | 1:3~1:4 | Negative | Online Inquiry |
TRUB1 Gene Knockout Cell Lines are genetically engineered cells that have been specifically modified to lack the TRUB1 gene, which plays a critical role in RNA processing and regulation. These cell lines are instrumental in investigating the biological functions of TRUB1 and its implications in various cellular processes, including gene expression regulation, mRNA stability, and cellular stress responses.
The primary function of TRUB1 Gene Knockout Cell Lines is to elucidate the role of TRUB1 in fundamental biological mechanisms through loss-of-function studies. By using CRISPR-Cas9 technology, researchers can achieve precise genetic alterations that facilitate detailed analyses of TRUB1’s contributions to processes such as alternative splicing, translation, and RNA decay. This allows for a clearer understanding of how TRUB1 impacts cellular health and disease states, thereby serving as a valuable model for studying conditions such as cancer, neurodegeneration, and other pathologies linked to RNA dysregulation.
The scientific importance of these knockout cell lines extends to both research and clinical applications. Researchers can utilize them to identify potential therapeutic targets or biomarkers related to TRUB1-mediated pathways. In clinical settings, this could translate into developing novel interventions aimed at correcting TRUB1-related dysfunctions, creating opportunities for more effective treatments.
TRUB1 Gene Knockout Cell Lines offer distinct advantages over traditional cell models. By allowing a more targeted approach to studying the effects of TRUB1 depletion, these cell lines enable researchers to obtain clearer, more reproducible results. Their ease of use in various in vitro experiments provides efficiency and reliability, making them a preferred choice for molecular and cellular biologists.
For researchers and clinicians, investing in TRUB1 Gene Knockout Cell Lines represents a significant opportunity to advance the understanding of gene function and its implications in human health. Our company brings a wealth of expertise in genetic engineering and cell line development, ensuring that our products meet the highest standards of quality and reliability. Thus, we are committed to supporting advancements in biological research and therapeutic discovery.
Please note that all services are for research use only. Not intended for any clinical use.
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