Gene: TRIM72
Official Full Name: tripartite motif containing 72provided by HGNC
Gene Summary: Enables identical protein binding activity. Predicted to be involved in several processes, including plasma membrane repair; proteasome-mediated ubiquitin-dependent protein catabolic process; and protein homooligomerization. Predicted to act upstream of or within negative regulation of insulin receptor signaling pathway; negative regulation of insulin-like growth factor receptor signaling pathway; and negative regulation of myotube differentiation. Predicted to be located in cytoplasmic vesicle membrane. Predicted to be active in cytoplasm and sarcolemma. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO13046 | TRIM72 Knockout cell line (HCT 116) | Human | TRIM72 | 1:2~1:4 | Negative | Online Inquiry |
TRIM72 Gene Knockout Cell Lines represent a cutting-edge tool in genetic research, designed to facilitate the investigation of the TRIM72 (Tripartite Motif-containing protein 72) gene involved in cellular processes such as muscle development and metabolic regulation. These genetically engineered cell lines are created through advanced CRISPR-Cas9 technology, allowing for specific and efficient disruption of the TRIM72 gene. As a result, researchers can study the downstream effects of gene loss on various physiological pathways, providing valuable insights into muscle biology and related metabolic disorders.
The primary function of these cell lines lies in their ability to mimic conditions of TRIM72 gene deficiency, thereby enabling the exploration of its role in cellular signaling, apoptosis, and muscle differentiation. By employing these knockout models, scientists can dissect the molecular mechanisms behind TRIM72’s function and its implications in diseases such as cardiomyopathy and type 2 diabetes. This specificity allows for targeted therapies to be developed, enhancing the translational value of research findings into clinical settings.
What sets TRIM72 Gene Knockout Cell Lines apart from conventional gene manipulation methods is their precision and efficacy, which reduce off-target effects commonly associated with earlier techniques. Additionally, these cell lines are extensively validated for performance, ensuring reproducibility and reliability, making them ideal for both academic and pharmaceutical research applications.
The value of TRIM72 Gene Knockout Cell Lines cannot be understated, as they empower researchers and clinicians to unlock new avenues in understanding complex biological questions, potentially leading to significant breakthroughs in therapeutic strategies. Our company prides itself on providing high-quality, state-of-the-art genetic tools, underpinned by a commitment to advancing scientific research and innovation in the field of molecular biology.
Please note that all services are for research use only. Not intended for any clinical use.
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