Gene: TRAPPC10
Official Full Name: trafficking protein particle complex subunit 10provided by HGNC
Gene Summary: The protein encoded by this gene is a transmembrane protein found in the cis-Golgi complex. The encoded protein is part of the multisubunit transport protein particle (TRAPP) complex and may be involved in vesicular transport from the endoplasmic reticulum to the Golgi. Mutations in this gene could be responsible for the Unverricht-Lundborg type of progressive myoclonus epilepsy, or for autoimmune polyglandular disease type 1. [provided by RefSeq, Jul 2008]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO34966 | TRAPPC10 Knockout cell line (HeLa) | Human | TRAPPC10 | 1:3~1:6 | Negative | Online Inquiry |
KO34967 | TRAPPC10 Knockout cell line (HCT 116) | Human | TRAPPC10 | 1:2~1:4 | Negative | Online Inquiry |
KO34968 | TRAPPC10 Knockout cell line (HEK293) | Human | TRAPPC10 | 1:3~1:6 | Negative | Online Inquiry |
KO34969 | TRAPPC10 Knockout cell line (A549) | Human | TRAPPC10 | 1:3~1:4 | Negative | Online Inquiry |
TRAPPC10 Gene Knockout Cell Lines are specifically engineered cellular models designed to enable researchers to investigate the functional roles of the TRAPPC10 gene, which is implicated in intracellular vesicular trafficking and various cellular processes. These knockout cell lines facilitate the study of gene function by providing a controlled environment in which the gene has been completely inactivated, allowing researchers to directly assess the impact of TRAPPC10 deficiency on cell physiology, signaling pathways, and overall cellular behavior.
The key mechanism behind the TRAPPC10 knockout involves CRISPR-Cas9 technology, which is widely recognized for its precision and efficiency in creating targeted gene disruptions. This method not only ensures the complete ablation of the TRAPPC10 gene but also leads to the study of phenotypic changes that can help clarify its biological significance. By utilizing these cell lines, researchers can further understand the implications of TRAPPC10 loss in conditions such as cancer, neurodegeneration, and metabolic disorders.
The scientific importance of TRAPPC10 gene knockout cell lines is evident in both basic and translational research. They serve as a powerful tool for gaining insights into the underlying mechanisms of diseases directly linked to TRAPPC10. Additionally, these models can significantly aid in drug discovery, specifically in identifying therapeutic targets and evaluating the efficacy of novel compounds.
One of the major advantages of the TRAPPC10 knockout cell lines over alternative models is their specificity and reliability. Unlike traditional gene silencing methods that may produce heterogeneous results, these knockout cell lines provide consistent and reproducible data, making them an essential resource for researchers seeking clarity in gene function studies.
Incorporating TRAPPC10 knockout cell lines into your research arsenal enhances your ability to unravel complex biological questions, making it invaluable for both academic and clinical applications. Furthermore, our company prides itself on delivering high-quality, rigorously validated biological products, supported by our extensive expertise in genetic engineering and cell line development. We are committed to empowering researchers and clinicians with tools that drive innovation and facilitate breakthroughs in understanding human health and disease.
Please note that all services are for research use only. Not intended for any clinical use.
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