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TPRA1 Knockout Cell Lines

Gene: TPRA1

Official Full Name: transmembrane protein adipocyte associated 1provided by HGNC

Gene Summary: Predicted to enable G protein-coupled receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Predicted to act upstream of or within embryonic cleavage and negative regulation of mitotic cell cycle phase transition. Predicted to be located in membrane. Predicted to be active in plasma membrane. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO00264 TPRA1 Knockout cell line (HeLa) Human TPRA1 1:3~1:6 Negative Online Inquiry
KO26559 TPRA1 Knockout cell line (HCT 116) Human TPRA1 1:2~1:4 Negative Online Inquiry
KO26560 TPRA1 Knockout cell line (HEK293) Human TPRA1 1:3~1:6 Negative Online Inquiry
KO26561 TPRA1 Knockout cell line (A549) Human TPRA1 1:3~1:4 Negative Online Inquiry

Background

TPRA1 Gene Knockout Cell Lines are scientifically engineered cellular models designed to precisely disrupt the function of the TPRA1 gene, a critical component in various biological signaling pathways. These knockout cell lines enable researchers to dissect the roles of TPRA1 in cellular processes, drug responses, and disease mechanisms, offering a robust platform for functional genomics studies.

The primary function of these cell lines revolves around the complete absence of TPRA1 protein, facilitating detailed investigations into its contributions to processes such as ion transport, cellular communication, and disease pathology. By employing techniques like CRISPR/Cas9 gene editing, these knockout lines provide a clean and validated system to analyze how the loss of TPRA1 affects cellular behavior and responses to therapeutics, making them invaluable for elucidating the gene's biological significance.

The significance of TPRA1 Gene Knockout Cell Lines in both research and clinical settings cannot be overstated. They serve as essential tools for drug discovery, enabling the assessment of therapeutic efficacy and safety through phenotype evaluation in a controlled environment. Additionally, these models can be instrumental in understanding genetic disorders associated with TPRA1 dysregulation, fostering the development of targeted treatments.

One of the unique selling points of our TPRA1 Gene Knockout Cell Lines is their high specificity and efficiency in gene disruption, surpassing transient or less targeted methods like RNA interference. This ensures researchers can rely on consistent and reproducible results, vital for rigorous scientific investigations. Our products also come with extensive documentation and protocols, supporting researchers at every stage of their work.

For researchers and clinicians focused on genetic and cellular studies, the TPRA1 Gene Knockout Cell Lines provide not just a tool, but a key to unlocking new insights into cell biology and disease treatment. Our company, dedicated to advancing biological research, leverages cutting-edge gene editing technologies and extensive expertise in cellular models, ensuring our offerings continually meet the evolving needs of the scientific community.

Please note that all services are for research use only. Not intended for any clinical use.

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