Gene: TPGS1
Official Full Name: tubulin polyglutamylase complex subunit 1provided by HGNC
Gene Summary: Predicted to enable microtubule binding activity and tubulin-glutamic acid ligase activity. Predicted to be involved in sperm axoneme assembly. Predicted to act upstream of or within several processes, including adult behavior; chemical synaptic transmission; and protein polyglutamylation. Located in centrosome. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO23316 | TPGS1 Knockout cell line (HeLa) | Human | TPGS1 | 1:3~1:6 | Negative | Online Inquiry |
KO23317 | TPGS1 Knockout cell line (HCT 116) | Human | TPGS1 | 1:2~1:4 | Negative | Online Inquiry |
KO23318 | TPGS1 Knockout cell line (HEK293) | Human | TPGS1 | 1:3~1:6 | Negative | Online Inquiry |
KO23319 | TPGS1 Knockout cell line (A549) | Human | TPGS1 | 1:3~1:4 | Negative | Online Inquiry |
TPGS1 Gene Knockout Cell Lines are specialized, genetically modified cell lines engineered for precise studies of the TPGS1 gene, which encodes a protein involved in the regulation of various cellular processes, including drug metabolism and transport. These models enable researchers to elucidate the functional roles of TPGS1 in health and disease by providing a reliable platform for next-generation genetic and pharmacological studies.
The primary function of TPGS1 Gene Knockout Cell Lines is to facilitate the investigation of TPGS1’s contributions to cellular responses, particularly in the context of pharmacokinetics and cellular stress responses. By completely knocking out the TPGS1 gene, these cell lines enable scientists to observe changes in drug absorption, distribution, metabolism, and excretion pathways, thus providing insights into the molecular underpinnings of drug-drug interactions and the factors that govern therapeutic efficacy.
In research and clinical settings, the TPGS1 knockout models are invaluable for drug discovery and development, particularly within oncology and personalized medicine fields. Understanding TPGS1’s role can enhance the development of targeted therapies and optimize treatment regimens, leading to improved patient outcomes. Moreover, these cell lines provide an efficient means to study genetic compensation mechanisms, further enhancing their application in investigating genetic pathways.
What sets TPGS1 Gene Knockout Cell Lines apart from alternatives is their high specificity and reliability. Unlike transient gene editing techniques, these stable knockout lines offer a consistent and reproducible system for long-term studies. Additionally, our commitment to quality and innovative genetic engineering techniques ensures that researchers receive cell lines that are meticulously characterized and validated, allowing for confident application in experiments.
For researchers and clinicians aiming to push the boundaries of biological knowledge and therapeutic advancements, TPGS1 Gene Knockout Cell Lines present a unique resource. Our expertise in cellular engineering and commitment to supporting scientific exploration underscores the value of our offerings, making us a trusted partner in the journey towards groundbreaking discoveries in molecular biology and pharmacology.
Please note that all services are for research use only. Not intended for any clinical use.
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