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TOR3A Knockout Cell Lines

Gene: TOR3A

Official Full Name: torsin family 3 member Aprovided by HGNC

Gene Summary: Enables ATP hydrolysis activity. Located in endoplasmic reticulum lumen. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO20888 TOR3A Knockout cell line (HeLa) Human TOR3A 1:3~1:6 Negative Online Inquiry
KO20889 TOR3A Knockout cell line (HCT 116) Human TOR3A 1:2~1:4 Negative Online Inquiry
KO20890 TOR3A Knockout cell line (HEK293) Human TOR3A 1:3~1:6 Negative Online Inquiry
KO20891 TOR3A Knockout cell line (A549) Human TOR3A 1:3~1:4 Negative Online Inquiry

Background

TOR3A Gene Knockout Cell Lines consist of advanced genetically modified cellular systems designed to specifically disrupt the TOR3A gene, which is implicated in various biological processes including signal transduction and cellular growth regulation. These cell lines have been engineered using cutting-edge CRISPR/Cas9 technology, which enables precise edits in the genome, allowing for comprehensive studies on the functional roles of the TOR3A gene in cellular behavior and disease models.

The primary mechanism of action involves the targeted introduction of double-strand breaks in the genomic DNA at the TOR3A locus, leading to frameshifts that result in a non-functional protein. This effective knockout approach allows researchers to observe phenotypic changes, signaling pathway alterations, and transcriptional modifications that could elucidate the TOR3A gene’s involvement in various diseases, including certain cancers and metabolic disorders. By utilizing these robust cell lines, scientists can delve deeper into the cellular mechanisms that underpin these conditions, facilitating a greater understanding of pathophysiology.

The scientific importance of TOR3A Gene Knockout Cell Lines is underscored by their versatility in applications ranging from basic biological research to preclinical drug discovery. They serve as invaluable tools for understanding gene function, screening potential therapeutic compounds, and developing precision medicine strategies. Moreover, these cell lines are crucial for high-throughput screenings in pharmaceutical research, promoting efficiency and accuracy in identifying novel drug targets.

What sets TOR3A Gene Knockout Cell Lines apart from traditional cell culture systems or less refined knockout models is their unparalleled specificity, reliability, and reproducibility. Unlike conventional methods, which may produce off-target effects, our product guarantees precise genetic modification, thus enhancing the validity of research outcomes. This heightened specificity is invaluable in both academic and industry settings, where there is a pressing need for accurate models that closely mimic in vivo conditions.

In summary, TOR3A Gene Knockout Cell Lines represent a significant advancement in genetic research and therapeutic development, offering researchers and clinicians a powerful platform to explore the complexities of gene function and its implications in health and disease. Our company’s expertise in genetic engineering and commitment to providing high-quality biological products ensures that you are equipped with the best tools to achieve your scientific goals.

Please note that all services are for research use only. Not intended for any clinical use.

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