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TNS2 Knockout Cell Lines

Gene: TNS2

Official Full Name: tensin 2provided by HGNC

Gene Summary: The protein encoded by this gene belongs to the tensin family. Tensin is a focal adhesion molecule that binds to actin filaments and participates in signaling pathways. This protein plays a role in regulating cell migration. Alternative splicing occurs at this locus and three transcript variants encoding three distinct isoforms have been identified. [provided by RefSeq, Jul 2008]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO29361 TNS2 Knockout cell line (HeLa) Human TNS2 1:3~1:6 Negative Online Inquiry
KO29362 TNS2 Knockout cell line (HCT 116) Human TNS2 1:2~1:4 Negative Online Inquiry
KO29363 TNS2 Knockout cell line (HEK293) Human TNS2 1:3~1:6 Negative Online Inquiry
KO29364 TNS2 Knockout cell line (A549) Human TNS2 1:3~1:4 Negative Online Inquiry

Background

TNS2 Gene Knockout Cell Lines are genetically modified cell lines specifically engineered to lack the TNS2 gene, a critical component implicated in various cellular processes, including signal transduction, cell adhesion, and the regulation of extracellular matrix composition. This knockout allows researchers to study the functional role of TNS2 in various biological contexts and its contributions to cellular behaviors and disease mechanisms.

The key function of these cell lines lies in their ability to model the effects of TNS2 absence in controlled laboratory conditions. By employing CRISPR-Cas9 technology, scientists can precisely disrupt the TNS2 gene, leading to observable phenotypic changes that aid in understanding its pathways and interactions. This mechanism empowers researchers to explore TNS2's involvement in processes such as cancer progression, fibrosis, and other pathologies, making these cell lines invaluable for investigative research.

The scientific importance of TNS2 Gene Knockout Cell Lines is underscored by their versatile applications in both fundamental and applied research settings. In basic research, they enable the dissection of molecular mechanisms driving disease models, while in clinical settings, they hold potential for studying targeted therapies and drug responses. This duality of relevance enhances their utility, attracting interest from academia and pharmaceutical companies alike.

Compared to alternative cell lines that may retain the TNS2 gene, these knockout lines provide a clean genetic background to study TNS2-associated pathways without confounding results stemming from gene expression variability. This specificity not only enhances experimental reliability but also accelerates the actionable insights derived from research findings.

For researchers, clinicians, and pharmaceutical developers, TNS2 Gene Knockout Cell Lines represent a significant advancement in the quest to elucidate the role of TNS2 in health and disease. By providing a robust platform for investigation, these cell lines can lead to novel therapeutic targets and enhance understanding of disease mechanisms.

With a wealth of experience in genetic engineering and a commitment to advancing biomedical research, our company stands at the forefront of developing high-quality biological products like TNS2 Gene Knockout Cell Lines, ensuring that researchers have the tools they need to achieve breakthrough discoveries.

Please note that all services are for research use only. Not intended for any clinical use.

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