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TNFAIP8L1 Knockout Cell Lines

Gene: TNFAIP8L1

Official Full Name: TNF alpha induced protein 8 like 1provided by HGNC

Gene Summary: Enables identical protein binding activity. Predicted to be involved in negative regulation of TOR signaling. Predicted to be active in cytoplasm. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO27400 TNFAIP8L1 Knockout cell line (HeLa) Human TNFAIP8L1 1:3~1:6 Negative Online Inquiry
KO27401 TNFAIP8L1 Knockout cell line (HCT 116) Human TNFAIP8L1 1:2~1:4 Negative Online Inquiry
KO27402 TNFAIP8L1 Knockout cell line (HEK293) Human TNFAIP8L1 1:3~1:6 Negative Online Inquiry
KO27403 TNFAIP8L1 Knockout cell line (A549) Human TNFAIP8L1 1:3~1:4 Negative Online Inquiry

Background

TNFAIP8L1 Gene Knockout Cell Lines are specially engineered cellular models that allow for the precise study of the TNFAIP8L1 gene's function by creating a complete loss of its expression. This gene, known for its involvement in various cellular processes, including apoptosis and inflammation, is critical in understanding the mechanisms underlying numerous diseases, such as cancer and autoimmune disorders. The knockout methodology utilizes CRISPR/Cas9 gene-editing technology, ensuring that the resulting cell lines are genetically stable and free from off-target mutations, providing researchers with reliable models for experimentation.

The primary function of TNFAIP8L1 Gene Knockout Cell Lines is to facilitate the investigation of the molecular pathways influenced by the TNFAIP8L1 gene. By observing the phenotypic and behavioral changes in these cells compared to wild-type counterparts, scientists can elucidate the gene’s role in cellular processes such as survival, proliferation, and response to stress signals. Furthermore, they can assess how its absence impacts therapeutic responses, making these cell lines invaluable in drug discovery and development.

The scientific importance of these knockout cell lines cannot be overstated. They serve as essential tools for basic research and translational studies, enabling innovations in targeted therapies for diseases where TNFAIP8L1 is implicated. Clinicians and researchers can utilize this product to gain insights into patient-specific responses to treatment, enhancing personalized medicine strategies.

Compared to conventional siRNA knockdown approaches, the TNFAIP8L1 Gene Knockout Cell Lines provide a permanent and stable model that eliminates the variability associated with transient gene silencing. This makes them a superior choice for long-term studies, reducing the need for repetitive validations and increasing the reliability of experimental outcomes.

For researchers and clinicians seeking a robust framework for studying the TNFAIP8L1 gene, these knockout cell lines offer an unmatched opportunity to deepen understanding and advance therapeutic strategies. By relying on our advanced genetic engineering capabilities and expertise in cell line development, our product stands at the forefront of providing high-quality biological tools that drive scientific discovery and clinical advancements.

Please note that all services are for research use only. Not intended for any clinical use.

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