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TMUB1 Knockout Cell Lines

Gene: TMUB1

Official Full Name: transmembrane and ubiquitin like domain containing 1provided by HGNC

Gene Summary: Involved in ERAD pathway. Predicted to be located in several cellular components, including centrosome; postsynaptic membrane; and recycling endosome. Predicted to be active in postsynaptic recycling endosome membrane. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO25432 TMUB1 Knockout cell line (HeLa) Human TMUB1 1:3~1:6 Negative Online Inquiry
KO25433 TMUB1 Knockout cell line (HCT 116) Human TMUB1 1:2~1:4 Negative Online Inquiry
KO25434 TMUB1 Knockout cell line (HEK293) Human TMUB1 1:3~1:6 Negative Online Inquiry
KO25435 TMUB1 Knockout cell line (A549) Human TMUB1 1:3~1:4 Negative Online Inquiry

Background

TMUB1 Gene Knockout Cell Lines are specialized, genetically engineered cellular models that contain a targeted deletion of the TMUB1 gene. This knockout cell line serves as a critical tool for studying the multifaceted roles of the TMUB1 protein in cellular processes, including its involvement in protein synthesis, stress response mechanisms, and regulation of cellular homeostasis. By disrupting the gene encoding TMUB1, researchers can observe the resulting phenotypic changes and gain insights into the protein's function, providing a clearer understanding of its biological significance.

The key mechanism underlying the utility of TMUB1 Gene Knockout Cell Lines lies in their ability to model the absence of TMUB1 in a controlled environment. This enables researchers to examine the cellular pathways affected by TMUB1 deletion, including alterations in cell proliferation, apoptosis, and metabolic activity. These lines are crucial for elucidating the TMUB1’s role in various pathological states, such as cancer and neurodegenerative diseases, thus offering a valuable platform for drug discovery and therapeutic development.

Scientifically, the applications of these knockout cell lines extend beyond basic research to clinical implications, where they can facilitate the identification of potential biomarkers and therapeutic targets. By employing TMUB1 knockout models, researchers have an enhanced capacity to investigate signaling pathways that may be disrupted in diseases, offering pathways for innovative treatment strategies.

Advantages of the TMUB1 Gene Knockout Cell Lines include their specificity and reproducibility, allowing for high-precision experimentation compared to alternative methods such as transient gene silencing techniques, which often lead to non-specific effects. Furthermore, these cell lines are fully characterized, ensuring that researchers can effectively integrate them into existing experimental frameworks without extensive validation processes.

For researchers and clinicians, the value of TMUB1 Gene Knockout Cell Lines lies in their potential to yield impactful data that could inform future studies and clinical applications. The ability to accurately model the absence of TMUB1 enhances experimental design, paving the way for novel discoveries that can translate into therapeutic insights.

Our company specializes in cutting-edge biological products, leveraging extensive expertise in genetic engineering to provide high-quality cell lines that empower the scientific community. As part of our commitment to advancing research, we ensure that our offerings meet the highest standards of quality and reliability, making them essential tools for innovative research.

Please note that all services are for research use only. Not intended for any clinical use.

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