Gene: TMEM79
Official Full Name: transmembrane protein 79provided by HGNC
Gene Summary: Enables identical protein binding activity. Predicted to be involved in several processes, including epithelial cell maturation; establishment of skin barrier; and positive regulation of epidermis development. Predicted to act upstream of or within cornification; cuticle development; and hair follicle morphogenesis. Predicted to be located in Golgi apparatus; lysosome; and membrane. Predicted to be active in lysosomal membrane and trans-Golgi network membrane. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO24959 | TMEM79 Knockout cell line (HeLa) | Human | TMEM79 | 1:3~1:6 | Negative | Online Inquiry |
KO24960 | TMEM79 Knockout cell line (HCT 116) | Human | TMEM79 | 1:2~1:4 | Negative | Online Inquiry |
KO24961 | TMEM79 Knockout cell line (HEK293) | Human | TMEM79 | 1:3~1:6 | Negative | Online Inquiry |
KO24962 | TMEM79 Knockout cell line (A549) | Human | TMEM79 | 1:3~1:4 | Negative | Online Inquiry |
TMEM79 Gene Knockout Cell Lines are specifically engineered cellular models that facilitate the study of the transmembrane protein 79 (TMEM79), which is implicated in various biological processes and disease mechanisms, including skin disorders and certain neurodegenerative conditions. These cell lines are created using CRISPR-Cas9 genome editing technology, resulting in precise ablation of the TMEM79 gene, thereby allowing researchers to analyze the effects of its absence on cellular function and disease phenotypes.
The primary function of TMEM79 is associated with cellular mechanisms involved in endosomal trafficking and lipid metabolism, making it an essential target for investigating its role in homeostasis and pathology. By leveraging these knockout cell lines, scientists can elucidate the consequences of TMEM79 depletion, from altered signaling pathways to changes in cellular morphology. This insight is particularly valuable in research settings focused on dermatological and neurological diseases, providing a robust model for understanding disease mechanisms and therapeutic avenues.
Compared to conventional cell lines, the TMEM79 Gene Knockout Cell Lines offer unparalleled specificity and reliability, enabling researchers to draw conclusive connections between TMEM79 and disease states. The precision of CRISPR technology ensures that off-target effects are minimal, enhancing the validity of experimental results. Moreover, the availability of these knockout lines addresses a critical gap in the study of TMEM79, which has historically been under-researched due to the lack of suitable models.
For researchers and clinicians, the TMEM79 Gene Knockout Cell Lines represent a significant opportunity to advance their understanding of gene function and its implications in disease. The potential to develop targeted therapies and conduct high-throughput screening assays makes these cell lines a valuable tool in both academic and industrial research environments.
Our company specializes in the development of cutting-edge biological products, ensuring that our offerings, such as the TMEM79 Gene Knockout Cell Lines, are supported by extensive research and a commitment to advancing scientific discovery.
Please note that all services are for research use only. Not intended for any clinical use.
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