Gene: TMEM47
Official Full Name: transmembrane protein 47provided by HGNC
Gene Summary: This gene encodes a member of the PMP22/EMP/claudin protein family. The encoded protein is localized to the ER and the plasma membrane. In dogs, transcripts of this gene exist at high levels in the brain. [provided by RefSeq, Jul 2008]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO25440 | TMEM47 Knockout cell line (HeLa) | Human | TMEM47 | 1:3~1:6 | Negative | Online Inquiry |
KO25441 | TMEM47 Knockout cell line (HEK293) | Human | TMEM47 | 1:3~1:6 | Negative | Online Inquiry |
TMEM47 Gene Knockout Cell Lines are a specialized product designed for researchers studying the functions and pathways of the TMEM47 gene, which is implicated in various biological processes, including cell signaling and membrane transport. These cell lines are generated using advanced CRISPR-Cas9 gene editing technology, leading to a precise and reliable knockout of the TMEM47 gene. By removing this gene, researchers can investigate its role in cellular homeostasis, stress responses, and potential links to diseases, particularly in oncology and neurobiology.
The primary mechanism of action of TMEM47 Gene Knockout Cell Lines revolves around the disruption of the TMEM47 gene's coding sequence, affecting downstream signaling pathways and membranous vesicle transport processes. This disruption allows for the analysis of phenotypic changes and provides insights into the gene's biological significance. Researchers can assess cellular responses, signaling alterations, and survival rates, thereby elucidating the potential therapeutic targets associated with TMEM47.
The scientific importance of these cell lines extends to their applications in both basic research and clinical settings. They can be utilized in drug discovery workflows, gene therapy explorations, and the study of disease mechanisms, enabling researchers to identify novel biomolecular interactions and therapeutic avenues. This product is positioned as a crucial tool in the quest to uncover the complexities of cellular functions and the genetic underpinnings of myriad diseases.
What sets TMEM47 Gene Knockout Cell Lines apart from alternative products is their high reliability, reproducibility, and the ability to generate specific models that closely mimic human pathophysiological conditions. Additionally, these cell lines go through rigorous validation processes to ensure consistent performance, relieving researchers from concerns about genetic variability commonly found in other knockout models.
In summary, the TMEM47 Gene Knockout Cell Lines present an invaluable resource for researchers and clinicians aimed at dissecting the role of this significant gene in cellular processes and disease pathology. Our company is dedicated to providing top-tier biological products, underpinned by a commitment to scientific excellence and innovation, ensuring that you have the tools necessary to advance your research and clinical applications.
Please note that all services are for research use only. Not intended for any clinical use.
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