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TMEM37 Knockout Cell Lines

Gene: TMEM37

Official Full Name: transmembrane protein 37provided by HGNC

Gene Summary: Predicted to enable calcium channel activity and voltage-gated monoatomic ion channel activity. Predicted to be involved in calcium ion transmembrane transport. Predicted to be located in membrane. Predicted to be part of monoatomic ion channel complex. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO25547 TMEM37 Knockout cell line (HeLa) Human TMEM37 1:3~1:6 Negative Online Inquiry
KO25548 TMEM37 Knockout cell line (HCT 116) Human TMEM37 1:2~1:4 Negative Online Inquiry
KO25549 TMEM37 Knockout cell line (HEK293) Human TMEM37 1:3~1:6 Negative Online Inquiry
KO25550 TMEM37 Knockout cell line (A549) Human TMEM37 1:3~1:4 Negative Online Inquiry

Background

TMEM37 Gene Knockout Cell Lines represent a cutting-edge tool in molecular biology, specifically designed for the investigation of gene function and the underlying mechanisms of disease. These cell lines are genetically engineered to have a targeted deletion of the TMEM37 gene, which encodes a protein implicated in cellular signaling and various physiological processes. By creating a model that lacks this specific gene, researchers can study the resulting phenotypic changes and elucidate the role of TMEM37 in cellular activities such as proliferation, differentiation, and apoptosis.

The key function of these knockout cell lines lies in their ability to provide a platform for functional assays, allowing scientists to explore not only the biological pathways involving TMEM37 but also its interactions with other cellular components. Importantly, understanding these pathways can lead to significant insights into the mechanisms of pathologies where TMEM37 is involved, such as certain cancers or metabolic disorders.

From a scientific standpoint, TMEM37 Gene Knockout Cell Lines are invaluable for both basic research and translational studies. They can be used for drug development, where the absence of TMEM37 may affect drug efficacy or resistance, thereby aiding in the identification of novel therapeutic targets. Additionally, they offer a robust model for high-throughput screening applications in pharmaceutical research.

One of the primary advantages of using TMEM37 Gene Knockout Cell Lines over conventional models is the precision offered by CRISPR/Cas9 technology, which ensures accurate and reproducible outcomes. This specificity reduces off-target effects common in earlier gene-editing methods, granting researchers greater confidence in their findings. Furthermore, these cell lines are readily available and optimized for various cell types, making them an adaptable choice for diverse experimental setups.

For researchers and clinicians seeking to enhance their understanding of TMEM37's functions and implications in health and disease, these knockout cell lines are a crucial resource. They not only facilitate pioneering research but also expedite the transition from laboratory discoveries to clinical applications. Our company prides itself on delivering high-quality, scientifically validated biological products, ensuring that our clients have the best tools available for their research endeavors.

Please note that all services are for research use only. Not intended for any clinical use.

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