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TMEM276 Knockout Cell Lines

Gene: TMEM276

Official Full Name: transmembrane protein 276provided by HGNC

Gene Summary: Predicted to enable zinc ion binding activity. Predicted to be located in membrane; nuclear envelope; and perinuclear region of cytoplasm. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO13166 TMEM276 Knockout cell line (HeLa) Human TMEM276 1:3~1:6 Negative Online Inquiry
KO13167 TMEM276 Knockout cell line (HCT 116) Human TMEM276 1:2~1:4 Negative Online Inquiry
KO13168 TMEM276 Knockout cell line (HEK293) Human TMEM276 1:3~1:6 Negative Online Inquiry
KO13169 TMEM276 Knockout cell line (A549) Human TMEM276 1:3~1:4 Negative Online Inquiry

Background

TMEM276 Gene Knockout Cell Lines are specialized cellular models engineered to lack the expression of the TMEM276 gene, a protein implicated in various physiological processes and potentially linked to several pathological conditions, including cancer progression and immunological responses. These knockout models allow researchers to investigate the functional role of TMEM276, providing a clearer understanding of its contributions to cellular behavior and disease mechanisms.

The key functions of TMEM276-derived cell lines involve examining changes in cell proliferation, migration, and signaling pathways when the gene is absent. By employing techniques such as CRISPR-Cas9 gene editing or RNA interference, the resultant cells enable detailed studies into how TMEM276 regulates important biological functions. Utilizing these knockout models, scientists can elucidate the pathways involved in tumorigenesis and immune modulation, facilitating the identification of potential therapeutic targets.

In research and clinical settings, the TMEM276 Gene Knockout Cell Lines serve as vital tools. Their applications extend from basic research, enabling the exploration of gene function, to translational studies, where they can model disease states for drug testing or biomarker discovery. These cell lines stand out in laboratory settings because they provide a controlled environment to observe the effects of TMEM276 ablation, offering insights that are often unattainable with traditional wild-type cells.

The advantages of these cell lines over alternatives include their precise genetic modification and the consistency of results, which are crucial for rigorous scientific inquiry. Additionally, the ease of use and the robustness of these models make them valuable for high-throughput screening and other advanced research methodologies.

Researchers and clinicians seeking to enhance their understanding of TMEM276's role in health and disease will find these knockout cell lines indispensable for driving discovery. They also exemplify our company’s commitment to advancing scientific knowledge, as we specialize in providing high-quality biological products that meet the evolving needs of the global research community. With our expertise and focus on innovation, we are dedicated to supporting groundbreaking discoveries in cellular biology and beyond.

Please note that all services are for research use only. Not intended for any clinical use.

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