Gene: TMEM184B
Official Full Name: transmembrane protein 184Bprovided by HGNC
Gene Summary: Predicted to enable transmembrane transporter activity. Predicted to be involved in transmembrane transport. Predicted to be active in membrane. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO01265 | TMEM184B Knockout cell line (COS-1) | Green monkey | TMEM184B | 1:3-1:4 | Negative | Online Inquiry |
KO28750 | TMEM184B Knockout cell line (HeLa) | Human | TMEM184B | 1:3~1:6 | Negative | Online Inquiry |
KO28751 | TMEM184B Knockout cell line (HCT 116) | Human | TMEM184B | 1:2~1:4 | Negative | Online Inquiry |
KO28752 | TMEM184B Knockout cell line (HEK293) | Human | TMEM184B | 1:3~1:6 | Negative | Online Inquiry |
KO28753 | TMEM184B Knockout cell line (A549) | Human | TMEM184B | 1:3~1:4 | Negative | Online Inquiry |
TMEM184B Gene Knockout Cell Lines are expertly engineered cellular models that allow researchers to investigate the functional role of the TMEM184B gene, which is implicated in various biological processes including cell signaling and membrane dynamics. These knockout cell lines are generated through precise genome editing techniques, such as CRISPR-Cas9, ensuring a complete and specific disruption of TMEM184B expression. As a result, they serve as invaluable tools for elucidating the gene's involvement in cellular pathways and disease states.
The key mechanism by which these knockout cell lines operate involves the complete absence of TMEM184B protein, leading to a phenotypic assessment that can reveal downstream effects on cellular behavior, including proliferation, differentiation, and response to stimuli. Furthermore, by comparing these knockout cells to their wild-type counterparts, researchers can gain insights into the gene's function in both normal and pathological conditions, thus facilitating understanding of diseases such as cancer and neurodegeneration.
The scientific importance of TMEM184B Gene Knockout Cell Lines extends into various research domains, including developmental biology, immunology, and cancer research. Their specific applications include drug discovery, where researchers can use these cells to test the efficacy of novel compounds targeting pathways influenced by TMEM184B.
What sets these cell lines apart from other alternatives is the enhanced specificity and reliability in disrupting gene function, reducing the risk of off-target effects commonly seen in earlier gene-editing methods. In addition, researchers benefit from the high-quality, validated lines that can be easily integrated into existing workflows, saving time and resources.
For researchers and clinicians alike, the ability to effectively study the implications of TMEM184B knockout contributes significant value, driving advancements in understanding disease mechanisms and therapeutic strategies. With a commitment to leading biotechnology innovation, our company provides industry-standard cell lines and technical support, empowering scientists to achieve impactful research outcomes.
Please note that all services are for research use only. Not intended for any clinical use.
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