Gene: TMEM17
Official Full Name: transmembrane protein 17provided by HGNC
Gene Summary: Involved in non-motile cilium assembly. Predicted to be located in ciliary membrane. Predicted to be part of MKS complex. Predicted to be active in ciliary transition zone. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO37900 | TMEM17 Knockout cell line (HeLa) | Human | TMEM17 | 1:3~1:6 | Negative | Online Inquiry |
KO37901 | TMEM17 Knockout cell line (HCT 116) | Human | TMEM17 | 1:2~1:4 | Negative | Online Inquiry |
KO37902 | TMEM17 Knockout cell line (HEK293) | Human | TMEM17 | 1:3~1:6 | Negative | Online Inquiry |
KO37903 | TMEM17 Knockout cell line (A549) | Human | TMEM17 | 1:3~1:4 | Negative | Online Inquiry |
TMEM17 Gene Knockout Cell Lines are specialized cellular models engineered to specifically disable the TMEM17 gene, which is implicated in various biological processes such as cell signaling, proliferation, and apoptosis. By creating knockout versions of this gene, researchers can leverage these cell lines to study the functional consequences of TMEM17 deficiency, elucidating its roles in cellular mechanisms and potentially its contributions to disease pathology.
The primary function of the TMEM17 Gene Knockout Cell Lines is to provide a controlled biological environment to investigate how the absence of TMEM17 affects cellular pathways. Through techniques such as CRISPR-Cas9 gene editing, these cell lines exhibit a complete knockdown of TMEM17, facilitating studies on cellular responses, growth behaviors, and interactions with other molecular players. Researchers can utilize these models to explore the gene's influence on disease models, particularly in cancer research and neurobiology, where TMEM17's roles in cellular communication and metabolic regulation are of great interest.
The scientific importance of these knockout cell lines lies in their applicability in both fundamental research and translational studies. Clinically, they allow scientists to discover potential therapeutic targets and mechanisms of action for drugs aimed at modulating TMEM17 pathways. Consequently, they serve as invaluable tools in drug development processes, enhancing insights into pharmacodynamics and toxicology.
In comparison to alternative models, TMEM17 Gene Knockout Cell Lines offer unparalleled specificity in the study of this particular gene. Many existing models may not accurately mimic the gene's absence or produce confounding results due to off-target effects. This precision ensures that findings are reliable and reproducible, making them vital for advancing scientific understanding.
For researchers and clinicians, these cell lines represent a significant advancement, as they open avenues for innovative research into key biological processes and their associated disorders. The ability to analyze TMEM17-related phenotypes in a controlled setting accelerates the potential for devising novel therapies and therapeutic strategies.
As a company committed to excellence in providing high-quality biological products, we specialize in the development and supply of meticulously validated cell lines tailored for cutting-edge research. With our expertise and dedication to advancing scientific discovery, we offer essential tools that empower researchers to push the boundaries of knowledge in genetics and cell biology.
Please note that all services are for research use only. Not intended for any clinical use.
If your question is not addressed through these resources, you can fill out the online form below and we will answer your question as soon as possible.
There is no product in your cart. |
CD Biosynsis is a leading customer-focused biotechnology company dedicated to providing high-quality products, comprehensive service packages, and tailored solutions to support and facilitate the applications of synthetic biology in a wide range of areas.