Gene: TMEM144
Official Full Name: transmembrane protein 144provided by HGNC
Gene Summary: Predicted to enable carbohydrate transmembrane transporter activity. Predicted to be involved in carbohydrate transmembrane transport. Predicted to be located in membrane. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO13247 | TMEM144 Knockout cell line (HeLa) | Human | TMEM144 | 1:3~1:6 | Negative | Online Inquiry |
KO13248 | TMEM144 Knockout cell line (HCT 116) | Human | TMEM144 | 1:2~1:4 | Negative | Online Inquiry |
KO13249 | TMEM144 Knockout cell line (HEK293) | Human | TMEM144 | 1:3~1:6 | Negative | Online Inquiry |
KO13250 | TMEM144 Knockout cell line (A549) | Human | TMEM144 | 1:3~1:4 | Negative | Online Inquiry |
TMEM144 Gene Knockout Cell Lines are precisely engineered cellular models that are designed to lack the functional TMEM144 gene, a membrane protein implicated in various cellular processes, including cell-cell interactions and signaling pathways. By utilizing advanced CRISPR/Cas9 gene-editing technology, these knockout cell lines enable researchers to investigate the physiological and pathological roles of the TMEM144 gene, providing invaluable insights into its contributions to human health and disease.
The primary mechanism of action for the TMEM144 Gene Knockout Cell Lines relies on the absence of TMEM144, allowing for the assessment of loss-of-function effects on cell behavior, gene expression profiles, and metabolic pathways. This enables scientists to study disease mechanisms, particularly in areas such as cancer, where aberrant cell signaling and interaction may underpin tumor progression.
The scientific importance of these cell lines is profound, as they serve as powerful tools in both basic research and translational medicine. They can aid in drug discovery, helping researchers identify new therapeutic targets, or elucidate the effects of potential compounds on cellular behavior without the confounding effects of TMEM144 expression. The versatility of these cell lines makes them suitable for a wide range of applications, including immunology, oncology, and regenerative medicine.
What sets TMEM144 Gene Knockout Cell Lines apart from alternative products is the high efficiency of gene editing and reliable performance in diverse experimental conditions. These cell lines are rigorously validated for consistency and reproducibility, ensuring that researchers can trust their findings. Additionally, they come with detailed characterization data that allows for rapid integration into various experimental setups.
For researchers and clinicians aiming to innovate in the understanding and treatment of diseases influenced by the TMEM144 gene, these knockout cell lines represent a significant advancement in experimental technology. Their value lies in their ability to streamline research workflows and enhance the rigor of scientific investigations.
As a leader in biological products, our company is committed to providing high-quality, well-characterized cell lines and supporting tools, backed by extensive expertise in genetics and cell biology, to facilitate breakthrough discoveries in biomedical research.
Please note that all services are for research use only. Not intended for any clinical use.
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